老年充血性心力衰竭：射血分数降低与射血分数保留的比较。
Congestive heart failure in the elderly: comparison between reduced ejection fraction and preserved ejection fraction.
机构信息
Division of Cardiovascular Medicine, Department of Integrated Medicine I, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
出版信息
J Cardiol. 2012 Mar;59(2):215-9. doi: 10.1016/j.jjcc.2011.11.014. Epub 2012 Jan 21.
BACKGROUND
Little has been known about clinical features and prognosis of very old patients with heart failure with preserved ejection fraction (HFPEF). The aim of this study was to compare clinical features and clinical outcomes between HFPEF and heart failure with reduced ejection fraction (HFREF) in patients older than 80 years.
METHODS
We enrolled a total of 113 patients over 80 years old, who were admitted for heart failure between 2006 and 2009. We retrospectively analyzed the clinical features including laboratory data and echocardiography parameters.
RESULTS
In 53 patients (49%) left ventricular ejection fraction was preserved. The clinical characteristics and treatment between HFPEF and HFREF showed that anemia was one of the risk factors for HFPEF, and the long-term outcomes of HFPEF in this population were not different from that of HFREF.
CONCLUSION
These results suggest that anemia is one of the important risk factors for HFPEF in the very elderly.
背景
对于射血分数保留的心力衰竭（HFPEF）的非常高龄患者的临床特征和预后知之甚少。本研究的目的是比较 80 岁以上患者中 HFPEF 和射血分数降低的心力衰竭（HFREF）之间的临床特征和临床结局。
方法
我们共纳入了 2006 年至 2009 年期间因心力衰竭住院的 113 名 80 岁以上的患者。我们回顾性分析了包括实验室数据和超声心动图参数在内的临床特征。
结果
在 53 名（49%）左心室射血分数正常的患者中，贫血是 HFPEF 的危险因素之一，该人群中 HFPEF 的长期预后与 HFREF 无差异。
结论
这些结果表明，贫血是高龄 HFPEF 的一个重要危险因素。
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