Girvin John P, Baeesa Saleh S
Department of Neurosciences, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia.
Neurosciences (Riyadh). 2006 Apr;11(2):72-7.
Hemispherectomy is the most successful operation for the control of seizures in a very select group of patients with infantile hemiplegia and intractable epilepsy. The efficacy of anatomical hemispherectomy has been offset to some degree by the fact that up to one third of those operated upon will subsequently develop obstructive hydrocephalus, and the so-called superficial subpial cerebral hemosiderosis, with potentially fatal complications. This review article details the operative technique of a modified functional hemispherectomy. In essence, the technique consists of removing the central (Rolandic) cortex and the temporal lobe of the affected hemisphere and leaving the remainder of the hemisphere intact, but neurogenically disconnected from the remaining brain.
大脑半球切除术是控制一小部分患有婴儿偏瘫和顽固性癫痫患者癫痫发作最成功的手术。解剖性大脑半球切除术的疗效在一定程度上被以下事实抵消：高达三分之一接受手术的患者随后会发生梗阻性脑积水，以及所谓的浅表软膜下脑铁沉积症，并伴有潜在的致命并发症。这篇综述文章详细介绍了改良“功能性”大脑半球切除术的手术技术。本质上，该技术包括切除患侧半球的中央（罗兰）皮质和颞叶，使半球的其余部分保持完整，但在神经方面与其余大脑断开连接。
