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[巴西南部一个城市性活跃年轻女性沙眼衣原体和淋病奈瑟菌感染的患病率]

[Prevalence of Chlamydia trachomatis and Neisseria gonorrhoea infections in sexual actives young women at a southern Brazilian city].

作者信息

Piazzetta Regina Celi Passagnolo Sérgio, de Carvalho Newton Sérgio, de Andrade Rosires Pereira, Piazzetta Giovana, Piazzetta Silvia Regina, Carneiro Rosangela

机构信息

Acadêmica de Pós-graduação Mestrado em Clínica Médica da Universidade Federal do Paraná – UFPR – Curitiba (PR), Brasil.

出版信息

Rev Bras Ginecol Obstet. 2011 Nov;33(11):328-33.

PMID:22267110
Abstract

PURPOSE

to determine the prevalence of Chlamydia and gonorrhea in a sample of women from Curitiba.

METHODS

this was a cross-sectional study with a sample of sexually active non-pregnant women aged between 16 and 23 years-old, with an intact uterus, with up to four sexual partners, without evidence of fever or purulent cervicitis, submitted to pelvic examination and PCR-based urine- testing for Chlamydia and gonorrhea. Exclusion criteria included: vaccination for HPV, vaccination history for the past 21 days, previous abnormal cytology, history of genital warts, splenectomy, immune disorders, and use of immunosuppressive drugs. An interview regarding sociodemographic and obstetric data and gynecological risk behavior for sexual transmitted diseases was applied. For statistical analysis, we used the χ(2) or Fisher's exact test to assess the association between variables.

RESULTS

the prevalence of Chlamydia and gonorrhea infection in the study group was 10.7 and 1.5%, respectively, and the rate of coinfection was 0.9%. No correlation was found between the age range of the volunteers, the onset of sexual activity, the number of sexual partners and of new sexual partners in the last six months, and the presence of Chlamydia or gonorrhea. In women who had vaginal discharge or ectropion, the prevalence of Chlamydia infection was two times higher than in those without such signs.

CONCLUSIONS

the results of this study were similar to national studies using PCR in urine samples for the detection of Chlamydia and gonorrhea in samples of non-pregnant women of the same age groups and with the same background. Since the volunteers with more than four sexual partners and those who had purulent endocervicitis were excluded, it is believed that the prevalence of Chlamydia and gonorrhea infection could have been greater in this population.

摘要

目的

确定库里蒂巴市女性样本中衣原体和淋病的患病率。

方法

这是一项横断面研究,样本为16至23岁性活跃的非妊娠女性,子宫完整,性伴侣不超过四个,无发热或脓性宫颈炎迹象,接受盆腔检查及基于聚合酶链反应(PCR)的尿液检测以筛查衣原体和淋病。排除标准包括:人乳头瘤病毒(HPV)疫苗接种、过去21天内的疫苗接种史、既往细胞学异常、尖锐湿疣病史、脾切除术、免疫紊乱以及使用免疫抑制药物。进行了关于社会人口学和产科数据以及性传播疾病妇科风险行为的访谈。对于统计分析,我们使用χ²检验或费舍尔精确检验来评估变量之间的关联。

结果

研究组中衣原体和淋病感染的患病率分别为10.7%和1.5%,合并感染率为0.9%。未发现志愿者的年龄范围、性活动开始时间、性伴侣数量以及过去六个月内新性伴侣数量与衣原体或淋病感染之间存在相关性。有白带或宫颈外翻的女性中,衣原体感染的患病率是无此类体征女性的两倍。

结论

本研究结果与国内使用PCR检测同年龄组、相同背景非妊娠女性样本中衣原体和淋病的研究结果相似。由于排除了性伴侣超过四个的志愿者以及有脓性宫颈炎的患者,据信该人群中衣原体和淋病感染的患病率可能更高。

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