Anokhina I P, Kogan B M, Man'kovskaia I V, Reshchikova E V, Stanishevskaia A V
Farmakol Toksikol. 1990 Jul-Aug;53(4):4-9.
The concept of the principal unity of the pivotal mechanisms underlying the formation of the syndrome of dependence on alcohol and various narcotic agents is presented. The central link of the mechanisms is the totality of the specific disturbances of neurochemical processes among which of particular importance are the specific changes in the functional state of catecholamine system. The theoretical approaches to the development of medicinal agents for treating alcoholism and drug addictions are considered. As an example there are discussed the results of using small doses of dopamine receptor stimulants (apomorphine and bromocriptine) and a neuropeptide cholecystokinin.
本文提出了酒精和各种麻醉剂依赖综合征形成背后关键机制的主要统一性概念。这些机制的核心环节是神经化学过程的特定紊乱总和，其中儿茶酚胺系统功能状态的特定变化尤为重要。文中还探讨了开发治疗酒精中毒和药物成瘾药物的理论方法。作为示例，讨论了使用小剂量多巴胺受体兴奋剂（阿扑吗啡和溴隐亭）和一种神经肽胆囊收缩素的结果。
