King's College London Division of Asthma, Allergy and Lung Biology Dept of Asthma, Allergy and Respiratory Science, King's College London School of Medicine, Bessemer Road, London, SE5 9PJ, UK.
Eur Respir J. 2012 Oct;40(4):977-81. doi: 10.1183/09031936.00163111. Epub 2012 Jan 20.
The parasternal intercostal muscle electromyogram (sEMGpara) is a measure of neural respiratory drive and reflects lung disease severity in stable cystic fibrosis (CF). The aim of the study was to measure sEMGpara in acute infective exacerbations of CF and compare changes in sEMGpara with those in conventional lung function measures. 12 patients with CF admitted to hospital with an acute chest infection were studied. There was a significant reduction in mean ± SD sEMGpara (ΔsEMGpara -38 ± 19%, p<0.001) between admission and discharge. Spirometery also improved significantly from admission to discharge; Δforced expiratory volume in 1 s % predicted 39 ± 30%, p<0.001 and Δvital capacity % pred 22 ± 18%, p<0.001. sEMGpara has potential value as a nonvolitional measure of change in respiratory function in CF.
胸旁肋间肌肌电图（sEMGpara）是一种衡量神经呼吸驱动的指标，可反映稳定期囊性纤维化（CF）患者的肺部疾病严重程度。本研究旨在测量 CF 急性感染加重期的 sEMGpara，并比较 sEMGpara 变化与常规肺功能测量的变化。12 例因急性胸部感染住院的 CF 患者参与了本研究。入院时与出院时相比，sEMGpara 的平均值显著降低（ΔsEMGpara-38±19%，p<0.001）。从入院到出院，肺活量测定法也显著改善；Δ用力呼气量占预计值的百分比为 39±30%（p<0.001），Δ肺活量占预计值的百分比为 22±18%（p<0.001）。sEMGpara 作为 CF 患者呼吸功能变化的非自主测量指标具有潜在价值。
