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应用多个Enterprise 支架重叠及弹簧圈栓塞技术治疗梭形或超宽颈环形动脉瘤的血管内重建治疗

Reconstructive endovascular treatment of fusiform or ultrawide-neck circumferential aneurysms with multiple overlapping enterprise stents and coiling.

机构信息

Department of Radiology, Samsung Medical Center, Sunkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

AJNR Am J Neuroradiol. 2012 May;33(5):965-71. doi: 10.3174/ajnr.A2857. Epub 2012 Jan 19.

Abstract

BACKGROUND AND PURPOSE

Fusiform aneurysms and ultrawide-neck circumferential aneurysms are still some of the most challenging lesions. The aim of this study was to investigate the efficacy and feasibility of the use of multiple overlapping Enterprise stents with coiling for the treatment of fusiform or ultrawide-neck circumferential aneurysms.

MATERIALS AND METHODS

Twelve consecutive patients (9 men and 3 women; mean age, 56 years) with fusiform (n = 5) or ultrawide-neck circumferential (n = 7) aneurysms were treated with 2-3 overlapping Enterprise stents and coiling. The feasibility of this procedure and the clinical and angiographic outcomes of this technique were retrospectively evaluated.

RESULTS

All patients were successfully treated by using this technique without any complications. Posttreatment angiographic results revealed grade 4 occlusion of the aneurysm in 6, grade 3 in 4, and grade 2 in 2 patients. Clinical follow-up was performed in all patients (mean, 16 months; range, 5-24 months). Nine patients had an mRS score of 0. Two had an mRS score of 1, one of whom had an initial mRS score of 2 due to the mass effect of a giant aneurysm; the other had a recurrent aneurysm presenting with SAH 5 years after clipping. Angiographic follow-up was performed in 10 patients at 6-20 months posttreatment. Nine had stable or improved occlusion, while 1 had a minor recurrence.

CONCLUSIONS

In this small series, multiple overlapping Enterprise stents with coiling were a feasible and effective option for the treatment of fusiform and ultrawide-neck circumferential aneurysms. Further experience and follow-up are required to document the long-term efficacy of this treatment.

摘要

背景与目的

梭形动脉瘤和超宽颈环形动脉瘤仍然是一些最具挑战性的病变。本研究旨在探讨使用多个重叠 Enterprise 支架结合线圈治疗梭形或超宽颈环形动脉瘤的疗效和可行性。

材料与方法

连续收治 12 例(9 例男性,3 例女性;平均年龄 56 岁)梭形(n=5)或超宽颈环形(n=7)动脉瘤患者,采用 2-3 个重叠 Enterprise 支架结合线圈治疗。回顾性评估该技术的可行性及临床和血管造影结果。

结果

所有患者均成功接受该技术治疗,无任何并发症。治疗后血管造影结果显示 6 例患者动脉瘤完全闭塞(grade 4),4 例患者部分闭塞(grade 3),2 例患者部分闭塞(grade 2)。所有患者均进行临床随访(平均 16 个月;范围 5-24 个月)。9 例患者 mRS 评分为 0。2 例患者 mRS 评分为 1,其中 1 例患者因巨大动脉瘤的占位效应初始 mRS 评分为 2,另 1 例患者在夹闭 5 年后因动脉瘤复发出现蛛网膜下腔出血。10 例患者在治疗后 6-20 个月进行血管造影随访。9 例患者闭塞稳定或改善,1 例患者出现轻微复发。

结论

在本小系列中,多个重叠 Enterprise 支架结合线圈是治疗梭形和超宽颈环形动脉瘤的一种可行且有效的选择。需要进一步的经验和随访来证明这种治疗的长期疗效。

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