Dasdag Suleyman, Akdag Mehmet Zulkuf, Kizil Goksel, Kizil Murat, Cakir Dilek Ulker, Yokus Beran
Department of Biophysics, Medical School of Dicle University, Diyarbakir, Turkey.
Electromagn Biol Med. 2012 Mar;31(1):67-74. doi: 10.3109/15368378.2011.624654. Epub 2012 Jan 23.
Recently, many studies have been carried out in relation to 900 MHz radiofrequency radiation (RF) emitted from a mobile phone on the brain. However, there is little data concerning possible mechanisms between long-term exposure of RF radiation and biomolecules in brain. Therefore, we aimed to investigate long-term effects of 900 MHz radiofrequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the rat brain. The study was carried out on 17 Wistar Albino adult male rats. The rat heads in a carousel were exposed to 900 MHz radiofrequency radiation emitted from a generator, simulating mobile phones. For the study group (n: 10), rats were exposed to the radiation 2 h per day (7 days a week) for 10 months. For the sham group (n: 7), rats were placed into the carousel and the same procedure was applied except that the generator was turned off. In this study, rats were euthanized after 10 months of exposure and their brains were removed. Beta amyloid protein, protein carbonyl, and malondialdehyde levels were found to be higher in the brain of rats exposed to 900 MHz radiofrequency radiation. However, only the increase of protein carbonyl in the brain of rats exposed to 900 MHz radiofrequency radiation was found to be statistically significant (p<0.001). In conclusion, 900 MHz radiation emitted from mobile/cellular phones can be an agent to alter some biomolecules such as protein. However, further studies are necessary.
最近，针对手机发出的900兆赫射频辐射（RF）对大脑的影响开展了许多研究。然而，关于长期暴露于射频辐射与大脑生物分子之间可能的作用机制的数据却很少。因此，我们旨在研究900兆赫射频辐射对大鼠大脑中β淀粉样蛋白、蛋白质羰基和丙二醛的长期影响。该研究以17只成年雄性Wistar白化大鼠为对象。将处于旋转木马装置中的大鼠头部暴露于模拟手机发出的900兆赫射频辐射下。对于研究组（n = 10），大鼠每天暴露于辐射下2小时（每周7天），持续10个月。对于假手术组（n = 7），将大鼠放入旋转木马装置中，除了关闭发生器外，应用相同的程序。在本研究中，暴露10个月后对大鼠实施安乐死并取出其大脑。结果发现，暴露于900兆赫射频辐射的大鼠大脑中β淀粉样蛋白、蛋白质羰基和丙二醛水平较高。然而，仅暴露于900兆赫射频辐射的大鼠大脑中蛋白质羰基的增加具有统计学意义（p<0.001）。总之，移动电话/蜂窝电话发出的900兆赫辐射可能是改变某些生物分子如蛋白质的一个因素。然而，还需要进一步研究。
