Department of Thoracic Surgery, The Affiliated First People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ann Thorac Surg. 2012 Feb;93(2):664-6. doi: 10.1016/j.athoracsur.2011.07.018.
Spontaneous rupture of a mediastinal germ cell tumor, while rare, is always accompanied by bleeding. In this report, we describe a case of a primary mediastinal mixed germ cell tumor that presented with bilateral massive hemothorax and hemorrhagic shock. An urgent thoracotomy, which was performed to control bleeding, confirmed bilateral hemothorax secondary to a ruptured mediastinal tumor. Pathologic diagnosis revealed the mediastinal tumor to be mixed choriocarcinoma and immature teratoma, with lung metastatic choriocarcinoma. The patient recovered well from the operation and received salvage chemotherapy. Two years after diagnosis, the patient remains in remission with no evidence of disease.
纵隔生殖细胞肿瘤自发性破裂虽不常见，但总是伴有出血。本报告描述了一例以双侧大量血胸和失血性休克为表现的原发性纵隔混合生殖细胞肿瘤。为控制出血而紧急进行的开胸手术证实双侧血胸是由纵隔肿瘤破裂引起的。病理诊断显示纵隔肿瘤为混合性绒毛膜癌和未成熟畸胎瘤，肺部转移性绒毛膜癌。患者术后恢复良好，并接受了挽救性化疗。诊断两年后，患者仍处于缓解期，无疾病证据。
