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优化根治性前列腺切除术以实现早期尿控恢复。

Optimizing radical prostatectomy for the early recovery of urinary continence.

机构信息

Cambridge University Hospital, Hills Road, Cambridge CB2 0QQ, UK.

出版信息

Nat Rev Urol. 2012 Jan 24;9(4):189-95. doi: 10.1038/nrurol.2012.2.

Abstract

Radical prostatectomy remains the gold-standard treatment for clinically localized prostate cancer. Although cancer control is the primary goal, secondary outcomes such as continence recovery are of great importance to patients. Thus, it is a challenge for prostate cancer surgeons to optimize continence outcomes without compromising oncologic results. Many high-volume surgeons have demonstrated excellent long-term continence rates in their patients, but early continence is variable and less than ideal even in expert hands. A plethora of individual technical maneuvers exist to optimize early recovery of continence, but as yet there is no composite technique that incorporates the relevant anatomic principles of minimizing damage to the urinary sphincters and their nerves, maximizing functional urethral length, creating a secure and watertight vesicourethral anastomosis, providing circumferential fascioligamentous support to the anastomosis and external sphincter, and ameliorating postoperative bladder descent. Our ten-step approach to collating these individual maneuvers into a unified technique could be used by surgeons to obtain the best possible early recovery of urinary control for their patients, without risking their oncologic outcomes.

摘要

根治性前列腺切除术仍然是治疗局限性前列腺癌的金标准。尽管癌症控制是主要目标,但对患者来说,控尿恢复等次要结果也非常重要。因此,前列腺癌外科医生面临的挑战是在不影响肿瘤学结果的情况下优化控尿效果。许多高容量外科医生在他们的患者中展示了出色的长期控尿率,但即使在专家手中,早期控尿也存在差异,并不理想。有很多单独的技术操作可以优化早期控尿的恢复,但迄今为止,还没有一种综合技术能够结合相关的解剖学原则,即最大限度地减少对尿道括约肌及其神经的损伤,最大限度地增加功能性尿道长度,建立安全和无泄漏的膀胱尿道吻合术,为吻合术和外括约肌提供环绕的筋膜韧带支持,并改善术后膀胱下降。我们将这些单独的操作整合为一个统一技术的十步方法,外科医生可以用来为患者获得尽可能好的早期尿控恢复,而不会危及他们的肿瘤学结果。

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