Kavvadias Tilemachos, Baessler Kaven, Schuessler Bernhard
Cantonal Hospital of Lucerne, Spitalstrasse 6210, Sursee, Lucerne, Switzerland.
Int Urogynecol J. 2012 May;23(5):553-61. doi: 10.1007/s00192-011-1649-z. Epub 2012 Jan 21.
Therapeutic options for chronic pelvic pain in women offer only a limited symptom relief. Especially in the patient with lower urinary tract symptoms (LUTS), where overlap of pain, storage and voiding symptoms is common, data on the efficacy of treatment of pain are limited. We conducted a literature review to detect articles which pertained to female patients with LUTS and pelvic pain and we included articles which evaluated the efficacy of the treatment of pelvic pain. Forty-one articles were detected, which included nerve stimulation (sacral and pudendal), intravesical instillations and injections, oral pharmacological treatments, periurethral injections as well as physical and manual therapy as treatment options. Only five controlled trials were found, which did not show superiority of the active treatment versus placebo. Although some treatment options show promising results in the treatment of pelvic pain in patients with LUTS, more randomised controlled trials are needed to confirm these results.
女性慢性盆腔疼痛的治疗选择只能提供有限的症状缓解。特别是在患有下尿路症状(LUTS)的患者中,疼痛、储尿和排尿症状重叠很常见,关于疼痛治疗效果的数据有限。我们进行了一项文献综述,以查找与患有LUTS和盆腔疼痛的女性患者相关的文章,并纳入了评估盆腔疼痛治疗效果的文章。共检测到41篇文章,其中包括神经刺激(骶神经和阴部神经)、膀胱内灌注和注射、口服药物治疗、尿道周围注射以及物理和手法治疗等治疗选择。仅发现5项对照试验,这些试验未显示积极治疗相对于安慰剂的优越性。尽管一些治疗选择在治疗LUTS患者的盆腔疼痛方面显示出有希望的结果,但仍需要更多的随机对照试验来证实这些结果。