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膀胱灌注在治疗膀胱疼痛综合征中的作用：对于既有膀胱疼痛又有 LUTS 的患者，膀胱内治疗是一种有效的选择吗？

The role of bladder instillation in the treatment of bladder pain syndrome: Is intravesical treatment an effective option for patients with bladder pain as well as LUTS?

机构信息

St Mary's Hospital, Imperial College NHS Trust, London, UK.

出版信息

Int Urogynecol J. 2020 Jul;31(7):1387-1392. doi: 10.1007/s00192-020-04303-7. Epub 2020 May 1.

DOI:10.1007/s00192-020-04303-7
PMID:32358624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7306012/
Abstract

The aetiology of bladder pain syndrome/interstitial cystitis is still unknown. Numerous mechanisms have been proposed and treatments targeting various aspects of these are used. This review looks at the existing evidence on bladder instillations and whether they could be used in the treatment of lower urinary tract symptoms as well.

摘要

膀胱疼痛综合征/间质性膀胱炎的病因仍不清楚。已经提出了许多机制，并且使用了针对这些机制各个方面的治疗方法。本文回顾了膀胱灌注的现有证据，以及它们是否可用于治疗下尿路症状。

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Histological evidence supports low anesthetic bladder capacity as a marker of a bladder-centric disease subtype in interstitial cystitis/bladder pain syndrome.组织学证据支持低麻醉膀胱容量作为间质性膀胱炎/膀胱疼痛综合征中以膀胱为中心的疾病亚型的一个标志物。
Int Urogynecol J. 2019 Nov;30(11):1863-1870. doi: 10.1007/s00192-019-04038-0. Epub 2019 Jun 28.
2
Outcomes of intravesical chondroitin-sulfate and combined hyaluronic-acid/chondroitin-sulfate therapy on female sexual function in bladder pain syndrome.膀胱疼痛综合征中膀胱内注射硫酸软骨素及透明质酸/硫酸软骨素联合治疗对女性性功能的影响
Int Urogynecol J. 2019 Nov;30(11):1857-1862. doi: 10.1007/s00192-019-04036-2. Epub 2019 Jun 28.
3
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Cross-over data supporting long-term antibiotic treatment in patients with painful lower urinary tract symptoms, pyuria and negative urinalysis.交叉试验数据支持对伴有疼痛性下尿路症状、脓尿且尿液分析呈阴性的患者进行长期抗生素治疗。
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Dimethyl sulfoxide (DMSO) as intravesical therapy for interstitial cystitis/bladder pain syndrome: A review.二甲基亚砜（DMSO）作为间质性膀胱炎/膀胱疼痛综合征的膀胱内治疗：综述。
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Which bladder instillations are more effective? DMSO vs. bupivacaine/heparin/triamcinolone: a retrospective study.哪种膀胱灌注更有效？二甲基亚砜与布比卡因/肝素/曲安奈德对比：一项回顾性研究。
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