American Urological Association Education and Research, Inc., Linthicum, Maryland, USA.
J Urol. 2011 Jun;185(6):2162-70. doi: 10.1016/j.juro.2011.03.064. Epub 2011 Apr 16.
To provide a clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome.
A systematic review of the literature using the MEDLINE® database (search dates 1/1/83-7/22/09) was conducted to identify peer reviewed publications relevant to the diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Insufficient evidence-based data were retrieved regarding diagnosis and, therefore, this portion of the Guideline is based on Clinical Principles and Expert Opinion statements. The review yielded an evidence base of 86 treatment articles after application of inclusion/exclusion criteria. These publications were used to create the majority of the treatment portion of the Guideline. When sufficient evidence existed, the body of evidence for a particular treatment was assigned a strength rating of A (high), B (moderate) or C (low). Additional treatment information is provided as Clinical Principles and Expert Opinion when insufficient evidence existed. See text and algorithm for definitions, and detailed diagnostic management, and treatment frameworks.
The evidence-based guideline statements are provided for diagnosis and overall management of interstitial cystitis/bladder pain syndrome as well as for various treatments. The panel identified first through sixth line treatments as well as developed guideline statements on treatments that should not be offered.
Interstitial cystitis/bladder pain syndrome is best identified and managed through use of a logical algorithm such as is presented in this Guideline. In the algorithm the panel identifies an overall management strategy for the interstitial cystitis/bladder pain syndrome patient. Diagnosis and treatment methodologies can be expected to change as the evidence base grows in the future.
为间质性膀胱炎/膀胱疼痛综合征的诊断和治疗提供临床框架。
使用 MEDLINE®数据库（搜索日期为 1983 年 1 月 1 日至 2009 年 7 月 22 日）进行了系统的文献复习，以确定与间质性膀胱炎/膀胱疼痛综合征的诊断和治疗相关的同行评议出版物。关于诊断，检索到的循证数据不足，因此本指南的这一部分基于临床原则和专家意见声明。应用纳入/排除标准后，该综述得出了 86 篇治疗文章的证据基础。这些出版物被用于创建指南治疗部分的大部分内容。当存在足够的证据时，特定治疗的证据体被分配为 A（高）、B（中）或 C（低）强度等级。当证据不足时，提供了更多的治疗信息，作为临床原则和专家意见。请参阅文本和算法，了解定义、详细的诊断管理和治疗框架。
提供了基于证据的指南声明，用于间质性膀胱炎/膀胱疼痛综合征的诊断和整体管理，以及各种治疗方法。该小组确定了一线至六线治疗方法，并制定了不应提供的治疗方法的指南声明。
通过使用本指南中提出的逻辑算法，最好识别和管理间质性膀胱炎/膀胱疼痛综合征。在该算法中，小组为间质性膀胱炎/膀胱疼痛综合征患者确定了整体管理策略。随着未来证据基础的增长，诊断和治疗方法预计会发生变化。
