Córdova María Olivia Noguez, Flores Ramírez Carlos I, Bejarano Benjamín Velasco, Arroyo Razo Gabriel A, Pérez Flores Francisco J, Tellez Vladimir Carranza, Ruvalcaba René Miranda
Department of Chemistry, Faculty of Superior Studies Cuautitlan, Field 1, Autonomous National University of Mexico, Av. May 1st s/n, Z. C. 54740, Cuautitlan Izcalli, State of Mexico, Mexico.
Int J Mol Sci. 2011;12(12):8575-80. doi: 10.3390/ijms12128575. Epub 2011 Nov 29.
In this work, the results of a study comparing the use of irradiation from different regions of the infrared spectrum for the promotion of several organic reactions, are presented and discussed. This use of eco-conditions provides a green approach to chemical synthesis. A set of ten different organic reactions were evaluated, including the Knoevenagel, Hantzsch, Biginelli and Meldrum reactions. It is important to highlight the use of a commercial device that produces infrared irradiation in the near infrared region and its distribution by convection providing heating uniformity, significantly reducing reaction times, achieving good yields and proceeding in the absence of solvent. It is also worth noting that a variety of different reactions may be performed at the same time. Finally, the products obtained were identified using TLC, together with corresponding MS-data, complementarily in comparison of NMR (1)H and (13)C data with literature information.
在这项工作中，展示并讨论了一项研究的结果，该研究比较了使用来自红外光谱不同区域的辐射来促进几种有机反应。这种生态条件的使用为化学合成提供了一种绿色方法。评估了一组十种不同的有机反应，包括Knoevenagel反应、Hantzsch反应、Biginelli反应和Meldrum反应。值得强调的是，使用了一种在近红外区域产生红外辐射的商业设备，并且通过对流进行分布以提供加热均匀性，显著缩短了反应时间，获得了良好的产率，并且在无溶剂的情况下进行反应。还值得注意的是，可以同时进行各种不同的反应。最后，使用薄层色谱法（TLC）以及相应的质谱数据对获得的产物进行了鉴定，并将核磁共振氢谱（¹H NMR）和碳谱（¹³C NMR）数据与文献信息进行互补比较。
