Marovt Maruska, El Shabrawi-Caelen Laila
*Department of Dermatovenerology, University Medical Centre Maribor, Maribor, Slovenia; and †Department of Dermatology, University Hospital Graz, Graz, Austria.
Am J Dermatopathol. 2015 Feb;37(2):e18-20. doi: 10.1097/DAD.0000000000000057.
Rare clinical variants of bullous pemphigoid (BP) include vesicular BP, dyshidrosiform BP, pemphigoid nodularis, seborrheic BP, pemphigoid vegetans, localized BP, erythrodermic BP, and juvenile BP. To our knowledge, this is the first report of an unusual case of purpuric BP. We present a case of 85-year-old white man who presented with a 2-week history of blisters and pruritic urticarial lesions all over his body. The diagnosis of purpuric BP was made on the basis of history, clinical presentation, histopathology report, direct and indirect immunofluorescence studies the diagnosis of purpuric BP was made. The reason for the development of palmoplantar purpuric lesions concomitant to ordinary patches and plaques of BP is unknown.
大疱性类天疱疮(BP)的罕见临床变体包括水疱型BP、汗疱疹样BP、结节性类天疱疮、脂溢性皮炎样BP、增殖性类天疱疮、局限性BP、红皮病型BP和青少年BP。据我们所知,这是首例紫癜性BP异常病例的报告。我们报告一例85岁白人男性,其全身出现水疱和瘙痒性荨麻疹样皮损,病程2周。根据病史、临床表现、组织病理学报告、直接和间接免疫荧光研究确诊为紫癜性BP。掌跖紫癜性皮损与BP的普通斑片和斑块同时出现的原因尚不清楚。