College of Chemistry, Beijing Normal University, Beijing, China.
Curr Pharm Des. 2012;18(8):1041-57. doi: 10.2174/138161212799315876.
Coronary artery disease (CAD) is the main cause of death and remains a major health problem worldwide. Myocardial perfusion imaging is a well established noninvasive method for assessing CAD. This review summarizes the development of various radiotracers for myocardial perfusion imaging, including single photon emission computed tomography (SPECT) perfusion imaging agents and positron emission tomography (PET) perfusion imaging agents and introduces novel basic research data related to this area. In addition, the current state of the art in myocardial perfusion imaging agents and the future direction are discussed in this review.
冠状动脉疾病（CAD）是死亡的主要原因，仍然是全球范围内的一个主要健康问题。心肌灌注成像是评估 CAD 的一种成熟的非侵入性方法。本综述总结了各种用于心肌灌注成像的放射性示踪剂的发展，包括单光子发射计算机断层扫描（SPECT）灌注成像剂和正电子发射断层扫描（PET）灌注成像剂，并介绍了该领域相关的新的基础研究数据。此外，本综述还讨论了心肌灌注成像剂的现状和未来方向。
