Johnson L N, Iseri O, Knodell R G
Division of Gastroenterology, University of Maryland School of Medicine, Baltimore.
Gastroenterology. 1990 Dec;99(6):1837-40. doi: 10.1016/0016-5085(90)90498-p.
A 68-year-old man presented with recurrent Hodgkin's lymphoma after a 9-year disease-free interval induced by chemotherapy. In addition to histological evidence of recurrent Hodgkin's disease, the liver biopsy specimen showed extensive caseating granulomas. Cultures of bone marrow and liver tissue tested negative for Mycobacterium tuberculosis. No antituberculous treatment was administered, and the patient had an excellent clinical response to additional chemotherapy for lymphoma. Hodgkin's lymphoma should be added to the list of disease entities associated with caseating granulomas in the liver.
一名68岁男性在化疗诱导的9年无病间隔期后出现复发性霍奇金淋巴瘤。除了复发性霍奇金病的组织学证据外，肝脏活检标本还显示有广泛的干酪样肉芽肿。骨髓和肝组织培养未检测到结核分枝杆菌。未给予抗结核治疗，该患者对淋巴瘤的额外化疗有良好的临床反应。霍奇金淋巴瘤应被列入与肝脏干酪样肉芽肿相关的疾病实体名单中。
