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改良双轨吻合术在近端胃切除术中的临床应用

Clinical application of modified double tracks anastomosis in proximal gastrectomy.

作者信息

Zhao Qun, Li Yong, Guo Weijia, Zhang Zhidong, Ma Zhixue, Jiao Zhikai

机构信息

Department of Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

Am Surg. 2011 Dec;77(12):1593-9.

Abstract

We compared the outcome of two surgical alimentary canal reconstruction methods after proximal gastrectomy. Three hundred ninety-six patients who underwent a radical proximal gastrectomy were randomized into two groups. Group A was treated with modified double tracks anastomosis, and Group B was treated with esophagus-remnant stomach direct anastomosis. Outcome measures were hematological indices, prognostic nutritional index (PNI), plasma hormone concentrations, and Visick index. The operative times in Groups A and B were 210 ± 53 and 150 ± 75 minutes and the hemorrhage volume was 173 ± 67 and 150 ± 75 mL, respectively. Six months after operation, values of hemoglobin concentration, body weights, and PNI indices were significantly increased in Group A compared with Group B. Levels of gastrin and somatostatin were obviously less than preoperative values and levels of cholecystokinin and motilin were significantly higher than preoperative values in both groups. All patients of Group A were classified into Visick index Grades I and II, whereas only 70.37 per cent of Group B belonged to Visick index Grades I and II postoperatively. The overall 3-year survival rate was not significantly different in both groups. Modified double tracks anastomosis as an alimentary canal reconstructive method for radical proximal gastrectomy showed better outcomes than esophagus-remnant stomach direct anastomosis.

摘要

我们比较了近端胃切除术后两种消化道重建手术方法的效果。396例行根治性近端胃切除术的患者被随机分为两组。A组采用改良双通道吻合术治疗,B组采用食管-残胃直接吻合术治疗。观察指标包括血液学指标、预后营养指数(PNI)、血浆激素浓度和Visick指数。A组和B组的手术时间分别为210±53分钟和150±75分钟,出血量分别为173±67毫升和150±75毫升。术后6个月,A组的血红蛋白浓度、体重和PNI指数值与B组相比显著升高。两组胃泌素和生长抑素水平明显低于术前值,胆囊收缩素和胃动素水平显著高于术前值。A组所有患者术后Visick指数均为Ⅰ级和Ⅱ级,而B组术后只有70.37%的患者属于Visick指数Ⅰ级和Ⅱ级。两组的3年总生存率无显著差异。改良双通道吻合术作为根治性近端胃切除术的消化道重建方法,效果优于食管-残胃直接吻合术。

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