Hart C, Wurm S, Hafner C, Andreesen R, Grube M
Abteilung für Hämatologie und Internistische Onkologie, Klinik für Innere Medizin I, Universitätsklinikum Regensburg.
Internist (Berl). 2012 Apr;53(4):467-73. doi: 10.1007/s00108-011-2996-z.
We report on a 72-year-old female patient with multiple myeloma who presented with alopecia and eye-catching alterations of the skin and the nails. A biopsy of the skin could confirm the diagnosis of immunoglobulin light chain (AL) amyloidosis, which was also suspected of having affected other organs. After six cycles of a cytoreductive therapy with bortezomib and dexamethasone a very good partial response of the multiple myeloma was seen and an improvement in the skin and nail alterations could be achieved.
我们报告了一名72岁的多发性骨髓瘤女性患者，该患者出现脱发以及皮肤和指甲的显著改变。皮肤活检确诊为免疫球蛋白轻链（AL）淀粉样变性，怀疑其他器官也受到影响。在接受了六个周期的硼替佐米与地塞米松的减瘤治疗后，多发性骨髓瘤出现了非常好的部分缓解，皮肤和指甲的改变也有所改善。
