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一名孕妇的颅骨血管肉瘤:病例报告及文献复习

Angiosarcoma of skull in a pregnant woman: case report and review of the literature.

作者信息

Samadian Mohammad, Rakhshan Mohammad, Haddadian Karim, Rezaei Omidvar, Zamani Seyed Ali Modaress, Khormaee Fatemeh

机构信息

Loghman-e-Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Department of Neurosurgery, Tehran, Islamic Republic of Iran.

出版信息

Turk Neurosurg. 2012;22(1):113-5. doi: 10.5137/1019-5149.JTN.3148-10.1.

DOI:10.5137/1019-5149.JTN.3148-10.1
PMID:22274983
Abstract

Angiosarcoma is a rare tumor of bone that uncommonly involves the skull. Primary neoplasms of the skull represent 2.6% of primary neoplasms of bone. We wish to report a case of angiosarcoma of he skull in an 18-year-old pregnant woman who presented with a rapidly growing left frontotemporal mass. Neuroimaging revealed a left frontotemporal mass with destruction of diploic space and both tables and with extension to the subgaleal and epidural spaces. The patient underwent surgery and the tumor was removed totally. Histological features of angiosarcoma were seen in the pathology study. She received adjuvant chemotherapy and radiation therapy. She has remained well during 6 years of follow-up with no evidence of recurrence. Angiosarcoma is a rare malignant bone tumor of vascular origin. Our case is the only female patient with skull angiosarcoma that has been reported so far.

摘要

血管肉瘤是一种罕见的骨肿瘤,很少累及颅骨。颅骨原发性肿瘤占骨原发性肿瘤的2.6%。我们希望报告一例18岁孕妇的颅骨血管肉瘤病例,该患者表现为左额颞部迅速生长的肿块。神经影像学检查显示左额颞部肿块,板障间隙和内外板均有破坏,并延伸至帽状腱膜下和硬膜外间隙。患者接受了手术,肿瘤被完全切除。病理研究显示有血管肉瘤的组织学特征。她接受了辅助化疗和放疗。在6年的随访中,她情况良好,没有复发迹象。血管肉瘤是一种罕见的血管源性恶性骨肿瘤。我们的病例是迄今为止报道的唯一一例患有颅骨血管肉瘤的女性患者。

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引用本文的文献

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Bone and soft tissue sarcomas during pregnancy: A narrative review of the literature.孕期骨肉瘤和软组织肉瘤:文献综述
J Adv Res. 2016 Jul;7(4):581-7. doi: 10.1016/j.jare.2016.01.003. Epub 2016 Feb 2.
2
Subdural hematoma caused by epithelioid angiosarcoma originating from the skull.起源于颅骨的上皮样血管肉瘤引起的硬脑膜下血肿。
Head Neck Pathol. 2013 Jun;7(2):159-62. doi: 10.1007/s12105-012-0389-9. Epub 2012 Jul 29.