Hindersin S, Schubert O, Cohnen M, Felsberg J, Schipper J, Hoffmann T K
Hals-Nasen-Ohren-Klinik, Universitätsklinikums Düsseldorf.
Laryngorhinootologie. 2008 May;87(5):345-8. doi: 10.1055/s-2007-995465.
Angiosarcoma of the temporal bone is an extremely rare malignant tumor, which originates from vascular endothelium. We describe a case of a 57-year-old woman, initially presenting with progressive hearing loss, otorrhea as well as facial palsy diagnosed as a mastoiditis elsewhere. After subtotal mastoidectomy histological examination revealed an angiosarcoma of the mastoid. Since the tumor was not completely removed lateral petrosectomy and postoperative radiotherapy were performed. Afterwards the patient developed local recurrence with intracerebral tumor extension. During palliative polychemotherapy the patient developed a pneumonia and deceased. In this manuscript the morphology, imaging characteristics and current treatment options of angiosarcomas of the lateral skull base are reviewed and discussed.
颞骨血管肉瘤是一种极其罕见的恶性肿瘤，起源于血管内皮。我们描述了一例57岁女性病例，最初表现为进行性听力丧失、耳漏以及面神经麻痹，在其他地方被诊断为乳突炎。在进行了乳突次全切除术后，组织学检查显示为乳突血管肉瘤。由于肿瘤未完全切除，遂进行了岩骨外侧切除术及术后放疗。之后，患者出现局部复发并伴有脑内肿瘤扩展。在姑息性多药化疗期间，患者发生肺炎并死亡。本文对侧颅底血管肉瘤的形态学、影像学特征及当前治疗选择进行了综述和讨论。
