Carkanat A I, Abdurrahman A, Abakay O, Cengizhan S, Selimoglu S H, Senyigit A
Department of Chest Disease, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Afr Health Sci. 2011 Sep;11(3):346-52.
Malignant pleural Mesothelioma (MPM) is a very rarely encountered tumor in the normal population.
To investigate the variations in incidence of MPM in Southeast region of Turkey.
We retrospectively investigated the data of 161 MPM patients who were diagnosed from January 2000 to December 2009. The residential areas were determined according to asbestos exposure which plays a role in MPM etiology; previously reported as having asbestos (Region 1) and asbestos has not been determined previously (Region 2).
One hundred nine (109) of the patients (67.7%) included from the Region 1 and 52 of them (32.3%) included from the Region 2. MPM incidence of the last decade was 3.9/100,000 person/year for the whole region. In Region 1, 2000-2004 incidences was 12.6/100,000 person/year and 2005-2009 incidences was 14.9/100,000 person/year. In Region 2, 2000-2004 incidences was 0.4/100,000 person/year and 2005-2009 incidences was 1.0/100,000 person/year. According to the recently conducted incidence studies in our region, MPM incidence increased in region 1 and decreased in region 2. The number of patients applying to our hospital has increased in the last three years.
This increase, in Region 1 may be associated with continuous use of asbestos.
恶性胸膜间皮瘤(MPM)在普通人群中是一种非常罕见的肿瘤。
调查土耳其东南部地区MPM的发病率变化。
我们回顾性研究了2000年1月至2009年12月期间确诊的161例MPM患者的数据。根据在MPM病因中起作用的石棉暴露情况确定居住区域;先前报告有石棉暴露的区域(区域1)和先前未确定有石棉暴露的区域(区域2)。
109例(67.7%)患者来自区域1,52例(32.3%)患者来自区域2。整个地区过去十年的MPM发病率为3.9/100,000人/年。在区域1,2000 - 2004年的发病率为12.6/100,000人/年,2005 - 2009年的发病率为14.9/100,000人/年。在区域2,2000 - 2004年的发病率为0.4/100,000人/年,2005 - 2009年的发病率为1.0/100,000人/年。根据我们地区最近进行的发病率研究,区域1的MPM发病率上升,区域2的发病率下降。在过去三年中,申请我院的患者数量有所增加。
区域1的这种上升可能与石棉的持续使用有关。