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本文引用的文献

1
Survival of pleural malignant mesothelioma in Italy: a population-based study.意大利胸膜恶性间皮瘤的生存率：一项基于人群的研究。
Int J Cancer. 2009 Jan 1;124(1):201-7. doi: 10.1002/ijc.23874.
2
Population based epidemiology and prognosis of mesothelioma in Leeds, UK.英国利兹间皮瘤的人群流行病学及预后情况
Thorax. 2008 May;63(5):435-9. doi: 10.1136/thx.2007.081430. Epub 2008 Jan 17.
3
Survival of malignant pleural mesothelioma cases in the Tuscan Mesothelioma Register, 1988-2000: a population-based study.托斯卡纳间皮瘤登记处1988 - 2000年恶性胸膜间皮瘤病例的生存率：一项基于人群的研究。
Eur J Cancer Prev. 2005 Jun;14(3):195-9. doi: 10.1097/00008469-200506000-00001.
4
Malignant mesothelioma due to environmental exposure to asbestos: follow-up of a Turkish cohort living in a rural area.因环境接触石棉导致的恶性间皮瘤：对居住在农村地区的土耳其队列的随访
Chest. 2002 Dec;122(6):2224-9. doi: 10.1378/chest.122.6.2224.
5
p53, p21 and metallothionein immunoreactivities in patients with malignant pleural mesothelioma: correlations with the epidemiological features and prognosis of mesotheliomas with environmental asbestos exposure.恶性胸膜间皮瘤患者中p53、p21和金属硫蛋白免疫反应性：与环境石棉暴露相关间皮瘤的流行病学特征及预后的相关性
Respir Med. 2001 Jul;95(7):588-93. doi: 10.1053/rmed.2001.1108.
6
Incidence in Izmir in 1993-1994: first results from Izmir Cancer Registry.1993 - 1994年伊兹密尔的发病率：伊兹密尔癌症登记处的初步结果。
Eur J Cancer. 2001 Jan;37(1):83-92. doi: 10.1016/s0959-8049(00)00355-5.
7
Incidence of malignant pleural mesothelioma due to environmental asbestos fiber exposure in the southeast of Turkey.土耳其东南部因环境中石棉纤维暴露导致的恶性胸膜间皮瘤发病率。
Respiration. 2000;67(6):610-4. doi: 10.1159/000056289.
8
Mesothelioma: cases associated with non-occupational and low dose exposures.间皮瘤：与非职业性和低剂量暴露相关的病例
Occup Environ Med. 1999 Aug;56(8):505-13. doi: 10.1136/oem.56.8.505.
9
Environmental asbestos exposure and malignant pleural mesothelioma.环境中石棉暴露与恶性胸膜间皮瘤
Respir Med. 1999 May;93(5):349-55. doi: 10.1016/s0954-6111(99)90318-9.
10
Malignant mesothelioma due to environmental exposure to erionite: follow-up of a Turkish emigrant cohort.因环境接触毛沸石导致的恶性间皮瘤：一个土耳其移民队列的随访
Eur Respir J. 1999 Mar;13(3):523-6. doi: 10.1183/09031936.99.13352399.

在安纳托利亚东南部地区，间皮瘤的发病率在过去二十年中并未下降。

The incidence of mesothelioma has not decreased for the last twenty years in Southeast region of Anatolia.

作者信息

Carkanat A I, Abdurrahman A, Abakay O, Cengizhan S, Selimoglu S H, Senyigit A

机构信息

Department of Chest Disease, Medical Faculty, Dicle University, Diyarbakir, Turkey.

出版信息

Afr Health Sci. 2011 Sep;11(3):346-52.

PMID:22275923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3260992/
Abstract

BACKGROUND

Malignant pleural Mesothelioma (MPM) is a very rarely encountered tumor in the normal population.

OBJECTIVES

To investigate the variations in incidence of MPM in Southeast region of Turkey.

METHODS

We retrospectively investigated the data of 161 MPM patients who were diagnosed from January 2000 to December 2009. The residential areas were determined according to asbestos exposure which plays a role in MPM etiology; previously reported as having asbestos (Region 1) and asbestos has not been determined previously (Region 2).

RESULTS

One hundred nine (109) of the patients (67.7%) included from the Region 1 and 52 of them (32.3%) included from the Region 2. MPM incidence of the last decade was 3.9/100,000 person/year for the whole region. In Region 1, 2000-2004 incidences was 12.6/100,000 person/year and 2005-2009 incidences was 14.9/100,000 person/year. In Region 2, 2000-2004 incidences was 0.4/100,000 person/year and 2005-2009 incidences was 1.0/100,000 person/year. According to the recently conducted incidence studies in our region, MPM incidence increased in region 1 and decreased in region 2. The number of patients applying to our hospital has increased in the last three years.

CONCLUSION

This increase, in Region 1 may be associated with continuous use of asbestos.

摘要

背景

恶性胸膜间皮瘤（MPM）在普通人群中是一种非常罕见的肿瘤。

目的

调查土耳其东南部地区MPM的发病率变化。

方法

我们回顾性研究了2000年1月至2009年12月期间确诊的161例MPM患者的数据。根据在MPM病因中起作用的石棉暴露情况确定居住区域；先前报告有石棉暴露的区域（区域1）和先前未确定有石棉暴露的区域（区域2）。

结果

109例（67.7%）患者来自区域1，52例（32.3%）患者来自区域2。整个地区过去十年的MPM发病率为3.9/100,000人/年。在区域1，2000 - 2004年的发病率为12.6/100,000人/年，2005 - 2009年的发病率为14.9/100,000人/年。在区域2，2000 - 2004年的发病率为0.4/100,000人/年，2005 - 2009年的发病率为1.0/100,000人/年。根据我们地区最近进行的发病率研究，区域1的MPM发病率上升，区域2的发病率下降。在过去三年中，申请我院的患者数量有所增加。

结论

区域1的这种上升可能与石棉的持续使用有关。