Okafor Christian I
Department of Physiology and Medicine, Faculty of Medical Sciences, University of Nigeria, Enugu Campus.
Indian J Endocrinol Metab. 2012 Jan;16(1):56-66. doi: 10.4103/2230-8210.91191.
Metabolic syndrome is a clustering of several cardiovascular risk factors. Contrary to earlier thoughts, metabolic syndrome is no longer rare in Africa. The prevalence is increasing, and it tends to increase with age. This increase in the prevalence of metabolic syndrome in the continent is thought to be due to departure from traditional African to western lifestyles. In Africa, it is not limited to adults but is also becoming common among the young ones. Obesity and dyslipidemia seem to be the most common occurring components. While obesity appears more common in females, hypertension tends to be more predominant in males. Insulin resistance has remained the key underlying pathophysiology. Though pharmacologic agents are available to treat the different components of the syndrome, prevention is still possible by reverting back to the traditional African way of life.
代谢综合征是多种心血管危险因素的聚集。与早期的认识相反，代谢综合征在非洲已不再罕见。其患病率正在上升，并且往往随着年龄增长而增加。该大陆代谢综合征患病率的上升被认为是由于从传统的非洲生活方式转向西方生活方式所致。在非洲，它不仅限于成年人，在年轻人中也变得普遍。肥胖和血脂异常似乎是最常见的组成部分。虽然肥胖在女性中似乎更常见，但高血压在男性中往往更为突出。胰岛素抵抗仍然是关键的潜在病理生理学机制。尽管有药物可用于治疗该综合征的不同组成部分，但通过回归传统的非洲生活方式仍有可能进行预防。
