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尼日利亚江户州奥奇地区孕妇代谢综合征的患病率及其决定因素

Prevalence of Metabolic Syndrome and Its Determinants in Pregnant Women in Auchi, Edo State, Nigeria.

作者信息

Uzochukwu Kierian Ikechukwu, Ugbenyen Anthony Moses, Ajayi Olulope Olufemi

机构信息

Department of Biochemistry, Edo State University, Uzairue Edo State, Nigeria.

出版信息

Rwanda J Med Health Sci. 2024 Nov 30;7(3):485-494. doi: 10.4314/rjmhs.v7i3.9. eCollection 2024 Nov.

Abstract

BACKGROUND

There are limited epidemiological data on metabolic syndrome (MetS) during gestation in many developing nations. Available information on MetS prevalence in pregnancy is of clinical importance as it could aid in identifying pregnant women at risk of adverse perinatal outcomes. This study was designed to determine the prevalence of MetS, and its associated risk factors in pregnant women in Auchi, Edo Stage, Nigeria.

METHODS

This hospital-based cross-sectional study involved 223 pregnant women aged 17-45 years recruited from selected hospitals in Auchi and its environs. Information on socio-demography and nutritional habits were obtained using a self-administered questionnaire. Anthropometric indices were determined using appropriate methods for height, weight and BMI. Blood glucose, triglyceride, high-density lipoprotein, low-density lipoprotein and total cholesterol were determined from the serum of the study participants using enzymatic assay. The prevalence of MetS was determined using the HNLBI/AHA and NECP ATP III definitions, modified for pregnant women.

RESULTS

The findings revealed the following prevalences: MetS 10.8%, low HDL 35.7%, obesity 14.4%, high blood pressure 4.5%, hyperglycaemia 21.6% and hypertriglyceridemia 11.8%. There was no significant association between social-demographic and life style parameters with MetS.

CONCLUSION

The findings emphasize the importance of vigilant monitoring of pregnant women to reduce the risk of metabolic syndrome.

摘要

背景

在许多发展中国家,关于妊娠期代谢综合征(MetS)的流行病学数据有限。妊娠期MetS患病率的现有信息具有临床重要性,因为它有助于识别有不良围产期结局风险的孕妇。本研究旨在确定尼日利亚江户州奥奇地区孕妇中MetS的患病率及其相关危险因素。

方法

这项基于医院的横断面研究纳入了223名年龄在17至45岁之间的孕妇,她们是从奥奇及其周边地区的选定医院招募的。使用自填问卷获取社会人口统计学和营养习惯方面的信息。采用适当方法测定身高、体重和BMI等人体测量指标。使用酶法从研究参与者的血清中测定血糖、甘油三酯、高密度脂蛋白、低密度脂蛋白和总胆固醇。采用针对孕妇修改后的美国国立卫生研究院心肺血液研究所/美国心脏协会(HNLBI/AHA)和美国国家胆固醇教育计划成人治疗组第三次报告(NECP ATP III)定义来确定MetS的患病率。

结果

研究结果显示以下患病率:MetS为10.8%,低HDL为35.7%,肥胖为14.4%,高血压为4.5%,高血糖为21.6%,高甘油三酯血症为11.8%。社会人口统计学和生活方式参数与MetS之间无显著关联。

结论

研究结果强调了对孕妇进行密切监测以降低代谢综合征风险的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd30/12110480/44b4e5beebb7/RJMHS0703-0485Fig1.jpg

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