Khadilkar Vaman V, Pandit Deepa S, Khadilkar Anuradha V, Chiplonkar Shashi A, Kinare Arun S
Hirabai Cowasji Jehangir Medical Research Institute, Sassoon Road, Pune, India.
Indian J Endocrinol Metab. 2012 Jan;16(1):124-33. doi: 10.4103/2230-8210.91207.
To study the effect of lifestyle intervention in the presence of multivitamin-zinc supplementation in improving the cardiometabolic status of overweight children.
Data were evaluated in 74 overweight children (11.3 ± 2.9 years) randomly assigned to three groups of intervention for 4 months as follows: group A: diet-exercise counseling with multivitamin-zinc supplementation; group B: diet-exercise counseling; and group C: placebo. Anthropometric, biochemical, carotid arterial and lifestyle parameters were assessed.
Lifestyle counseling resulted in significant reduction in inactivity, energy and fat intakes and increase in micronutrient density of diets and physical activity in groups A and B in comparison to group C. Percent decline in body fat was more in group A than in groups B and C. Percent change in triglycerides (-13.7%) was significantly higher in group A than in groups B (-5.9%) and C (5.7%). Pulse wave velocity and elasticity modulus reduced and arterial compliance improved significantly in group A than in group B.
Multivitamin-zinc supplementation with lifestyle intervention has a positive effect of on the cardiometabolic status of overweight children.
研究在补充多种维生素 - 锌的情况下进行生活方式干预对改善超重儿童心脏代谢状况的影响。
对74名超重儿童（11.3±2.9岁）的数据进行评估，这些儿童被随机分为三组，进行为期4个月的干预，如下：A组：饮食 - 运动咨询并补充多种维生素 - 锌；B组：饮食 - 运动咨询；C组：安慰剂。评估人体测量学、生化、颈动脉和生活方式参数。
与C组相比，生活方式咨询使A组和B组的不活动时间、能量和脂肪摄入量显著减少，饮食中的微量营养素密度和身体活动增加。A组的体脂下降百分比高于B组和C组。A组甘油三酯的变化百分比（-13.7%）显著高于B组（-5.9%）和C组（5.7%）。与B组相比，A组的脉搏波速度和弹性模量降低，动脉顺应性显著改善。
补充多种维生素 - 锌并结合生活方式干预对超重儿童的心脏代谢状况有积极影响。
