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[淋菌性感染的临床流行病学特征及抗菌药物耐药模式]

[Clinico-epidemiological features and antimicrobial resistance pattern in gonococcal infection].

作者信息

Bădescu Aida Corina, Duca Elena, Brănişteanu Daciana Elena, Dobre C, Solovăstru Laura Gheucă, Stătescu Laura, Stoleru Gabriela, Vasîlca A, Vâţă D, Petrescu Zenaida

机构信息

Universităţii de Medicină şi Farmacie "Gr. T. Popa" Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2011 Oct-Dec;115(4):1237-42.

PMID:22276476
Abstract

AIM

To analyze clinical and epidemiological features in patients with gonococcal infection attended Dermato-Venerology Clinic in Iasi and regional dermato-venerology offices and to evaluate gonococcal antimicrobial resistance pattern.

METHODS

The study was carried out on 129 patients clinically diagnosed and bacteriologically confirmed with gonococcal infection who were subsequently submitted to a questionnaire. We studied their demographic characteristics (sex, age, nationality, marital status), clinical features (site of infection, symptoms, concurrent STI, previous history of gonorrhoea) and behavioral aspects (education, number and type of sexual partners, safe sexual practices).

RESULTS

We found in our patients a strong association of gonorrhoea with young male individual, poor educational level and with clinical symptoms of urethritis. The level of antimicrobial resistance is higher than in other European countries.

CONCLUSIONS

The poor health-seeking behavior, symptoms not specific enough, resistance pattern, lack of accessible and sensitive diagnostic methods lead to undiagnosed and probably mistreated gonorrhoea.

摘要

目的

分析在雅西皮肤性病诊所及地区皮肤性病办公室就诊的淋病感染患者的临床和流行病学特征,并评估淋病奈瑟菌的抗菌药物耐药模式。

方法

对129例临床诊断并经细菌学证实为淋病感染的患者进行了研究,随后对他们进行了问卷调查。我们研究了他们的人口统计学特征(性别、年龄、国籍、婚姻状况)、临床特征(感染部位、症状、并发性传播感染、既往淋病病史)和行为方面(教育程度、性伴侣数量和类型、安全性行为)。

结果

我们发现患者中淋病与年轻男性个体、低教育水平以及尿道炎临床症状密切相关。抗菌药物耐药水平高于其他欧洲国家。

结论

就医行为不佳、症状不够特异、耐药模式、缺乏可及且敏感的诊断方法导致淋病未被诊断且可能治疗不当。

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