School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
Int J Paediatr Dent. 2012 Nov;22(6):459-66. doi: 10.1111/j.1365-263X.2011.01217.x. Epub 2012 Jan 25.
This in vitro study aimed to test the performance of fluorescence-based methods in detecting occlusal caries lesions in primary molars compared to conventional methods.
Two examiners assessed 113 sites on 77 occlusal surfaces of primary molars using three fluorescence devices: DIAGNOdent (LF), DIAGNOdent pen (LFpen), and fluorescence camera (VistaProof-FC). Visual inspection (ICDAS) and radiographic methods were also evaluated. One examiner repeated the evaluations after one month. As reference standard method, the lesion depth was determined after sectioning and evaluation in stereomicroscope. The area under the ROC curve (Az), sensitivity, specificity, and accuracy of the methods were calculated at enamel (D1) and dentine caries (D3) lesions thresholds. The intra and interexaminer reproducibility were calculated using the intraclass correlation coefficient (ICC) and kappa statistics.
At D1, visual inspection presented higher sensitivities (0.97-0.99) but lower specificities (0.18-0.25). At D3, all the methods demonstrated similar performance (Az values around 0.90). Visual and radiographic methods showed a slightly higher specificity (values higher than 0.96) than the fluorescence based ones (values around 0.88). In general, all methods presented high reproducibility (ICC higher than 0.79).
Although fluorescence-based and conventional methods present similar performance in detecting occlusal caries lesions in primary teeth, visual inspection alone seems to be sufficient to be used in clinical practice.
本体外研究旨在检测与传统方法相比,基于荧光的方法在检测乳牙咬合面龋损中的性能。
两名检查者使用三种荧光设备(DIAGNOdent(LF)、DIAGNOdent 笔(LFpen)和荧光相机(VistaProof-FC))评估了 77 颗乳牙的 113 个咬合面。还评估了目视检查(ICDAS)和放射学方法。一名检查者在一个月后重复评估。作为参考标准方法,在体视显微镜下评估和切片后确定病变深度。计算了方法在釉质(D1)和牙本质龋(D3)病变阈值下的 ROC 曲线下面积(Az)、敏感性、特异性和准确性。使用组内相关系数(ICC)和 Kappa 统计评估了内部和内部检查者的可重复性。
在 D1 时,目视检查具有较高的敏感性(0.97-0.99),但特异性较低(0.18-0.25)。在 D3 时,所有方法的表现相似(Az 值约为 0.90)。目视和放射学方法的特异性略高于基于荧光的方法(值高于 0.96),而后者的特异性约为 0.88。一般来说,所有方法的重复性都很高(ICC 高于 0.79)。
尽管基于荧光的方法和传统方法在检测乳牙咬合面龋损方面具有相似的性能,但单独使用目视检查似乎足以在临床实践中使用。