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[作为脑症状和综合征病因的心脏病]

[Heart diseases as a cause of cerebral symptoms and syndromes].

作者信息

Herrschaft H

机构信息

Neurologische Klinik des Niedersächsischen Landeskrankenhauses, Lüneburg.

出版信息

Fortschr Neurol Psychiatr. 1990 Aug;58(8):287-300. doi: 10.1055/s-2007-1001192.

DOI:10.1055/s-2007-1001192
PMID:2227759
Abstract

The causes, clinical indications and diagnosis and differential diagnosis of cardiac disorders which may lead to cerebral symptoms are illustrated on the basis of a review of the present day level of scientific research. Principally involved are cerebral ischaemias arising from cerebral embolisms or from reduction of cardiac output in cardiovalvular and myocardial disorders. The incidence of all embolisms of cardiac origin makes up 10% of all ischaemic cerebral infarcts, with auricular fibrillation, irrespective of its origin, mitral stenosis, myocardial infarct, mitral insufficiency and combined mitral valve defects, and, in younger patients, mitral valve prolapse, being, in this order of frequency, of primary clinical significance. The other cardiovalvular and myocardial disorders have, in comparison, a relatively low incidence of cerebral embolisms. Haemodynamically induced cerebral ischaemias frequently occur in the form of complications following acute cardiac arrest, in myocarditis and in case of primary cardiomyopathies resulting from cardiac insufficiency or complicating bradyarrhythmia. They are clinically apparent in the form of syncope, and other impairments of consciousness of various levels of seriousness with and without indications of cerebral origin, extending up to coma. In view of the high incidence of 25% of acute cerebral ischaemias in cases of cardiac disease, not only neurological but also detailed cardiological investigation is vital in all cases for a correct diagnosis and for the selection of a suitable course of treatment. Cerebral complications in bradyarrhythmia and endocarditis are discussed in the context of a review of the relevant literature together with consideration of their epidemiology, aetiology, pathophysiology and clinical profile. Pathological sinus-bradycardia, bradyarrhythmia absoluta, sinu-atrial and atrio-ventricular blockages, carotid-sinus and sick-sinus node syndrome, paroxysmal atrial tachycardia, AV-node tachycardias, and auricular fibrillation and flutter, taken as a whole, lead to cerebral complications affected patients in 5 to 10% of afflictions of the central nervous system occur in 50% of patients suffering from complete AV blockage and, at a not precisely definable frequency, in patients suffering from other bradyarrhythmias. In addition to transitory, uncharacteristic symptoms such as dizziness, vertigo, impairment of vision and balance, presyncope, syncope and Adams-Stokes syndrome dominate the clinical profile. Endocarditis, with an incidence of 0.01 to 0.05% in the overall population, results in central nervous system complications in 12 to 25% of cases on average.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

基于对当前科研水平的综述,阐述了可能导致脑部症状的心脏疾病的病因、临床指征以及诊断和鉴别诊断。主要涉及因脑栓塞或心脏瓣膜及心肌疾病导致的心输出量减少引起的脑缺血。所有心脏源性栓塞的发生率占所有缺血性脑梗死的10%,心房颤动(无论其病因)、二尖瓣狭窄、心肌梗死、二尖瓣关闭不全和二尖瓣联合瓣膜缺损,以及在年轻患者中,二尖瓣脱垂,按此频率顺序,具有主要临床意义。相比之下,其他心脏瓣膜和心肌疾病的脑栓塞发生率相对较低。血流动力学诱导的脑缺血常以急性心脏骤停、心肌炎以及因心脏功能不全或并发缓慢性心律失常导致的原发性心肌病后的并发症形式出现。它们在临床上表现为晕厥以及其他不同严重程度的意识障碍,有或无脑部起源的迹象,直至昏迷。鉴于心脏疾病患者中急性脑缺血的发生率高达25%,不仅进行神经学检查,而且进行详细的心脏病学检查对于正确诊断和选择合适的治疗方案在所有病例中都至关重要。在回顾相关文献并考虑其流行病学、病因学、病理生理学和临床特征的背景下,讨论了缓慢性心律失常和心内膜炎中的脑部并发症。病态窦房结综合征、完全性缓慢性心律失常、窦房结和房室传导阻滞、颈动脉窦和病态窦房结综合征、阵发性房性心动过速、房室结性心动过速以及心房颤动和扑动,总体而言,在5%至10%的中枢神经系统疾病患者中导致脑部并发症,在50%的完全性房室传导阻滞患者中出现,在其他缓慢性心律失常患者中出现频率不确切。除了短暂的、无特征性的症状如头晕、眩晕、视力和平衡障碍、晕厥前状态、晕厥和阿-斯综合征外,这些症状在临床特征中占主导地位。心内膜炎在总体人群中的发生率为0.01%至0.05%,平均在12%至25%的病例中导致中枢神经系统并发症。(摘要截断于400字)

相似文献

1
[Heart diseases as a cause of cerebral symptoms and syndromes].[作为脑症状和综合征病因的心脏病]
Fortschr Neurol Psychiatr. 1990 Aug;58(8):287-300. doi: 10.1055/s-2007-1001192.
2
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1
Distribution of ischemic cerebrovascular events in cardiac embolism.
Klin Wochenschr. 1991 Oct 18;69(16):757-62. doi: 10.1007/BF01797614.