Sarrami Amir Hossein, Setareh Mehrdad, Afshar-Moghaddam Noushin, Izadinejad Masoud, Saadatnia Mohammad
Medical Student, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2011 Jul;16(7):968-73.
We describe a case of intracranial malignant fibrous histiocytoma which had infiltrated pons, cerebellum and basal surface of left temporal lobe without any visible mass. The patient presented with a sudden loss of consciousness and vomiting. Clinical findings, laboratory tests, imaging and examination of the cerebrospinal fluid tended to establish the diagnosis of an infectious condition than a malignancy. Without any response to the antibiotics and with a progressive deterioration of neurologic and mental condition, the patient died after 20 days. In the autopsy, histological and immunohistochemical study of the brain revealed the diagnosis of malignant fibrous histiocytoma (MFH).
我们描述了一例颅内恶性纤维组织细胞瘤，该肿瘤已浸润脑桥、小脑和左颞叶底面，未发现任何可见肿块。患者出现突发意识丧失和呕吐。临床症状、实验室检查、影像学检查及脑脊液检查结果更倾向于诊断为感染性疾病而非恶性肿瘤。在使用抗生素治疗无效且神经和精神状况逐渐恶化后，患者于20天后死亡。尸检时，对脑部进行的组织学和免疫组织化学研究确诊为恶性纤维组织细胞瘤（MFH）。
