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[栖息于天然放射性增强地区的苔原田鼠(Microtus oeconomus Pall.)血液中红细胞脂质的特征]

[Characteristics of erythrocyte lipids in blood of tundra voles (Microtus oeconomus Pall.) inhabiting areas with increased natural radioactivity].

作者信息

Shevchenko O G, Shuktomova I I, Shishkina L N

出版信息

Radiats Biol Radioecol. 2011 Sep-Oct;51(5):624-32.

Abstract

Interrelations between the lipid characteristics of the blood erythrocytes and 226Ra accumulation in the body of tundra voles (Microtus oeconomus Pall.) inhabiting areas with different levels of the radiation background were investigated. It is shown that the ratio of the phospholipid (PL) fractions which cause the blood erythrocyte structure depends on the phase of the population cycle, as well as on the sex and age of tundra voles. The statistically significant interrelation between lysoforms and the sphingomielin content has been revealed in the blood erythrocyte PL of tundra voles; its scale somewhat differs for the animals from the reference and Ra areas. The peroxide concentration in the blood erythrocyte lipids of tundra voles from the Ra area exceeded the control values in all mature groups of the animals trapped at the depression phase of the population density. The 226Ra content in the bodies of the tundra voles which were trapped in the Ra area at the increased phase of the population cycle is for certain higher than that for the animals from the reference area. Interrelations between the lipid peroxidation parameters in the blood erythrocytes and the body 226Ra content for separate sex-age groups of tundra voles have been revealed.

摘要

研究了居住在不同辐射本底水平地区的苔原田鼠(Microtus oeconomus Pall.)体内血液红细胞脂质特征与226镭积累之间的相互关系。结果表明,决定血液红细胞结构的磷脂(PL)组分比例取决于种群周期阶段,以及苔原田鼠的性别和年龄。在苔原田鼠的血液红细胞PL中,已揭示出溶血形式与鞘磷脂含量之间具有统计学意义的相互关系;来自对照区和镭污染区的动物,这种关系的程度略有不同。在种群密度下降阶段捕获的所有成年组苔原田鼠中,来自镭污染区的动物血液红细胞脂质中的过氧化物浓度超过了对照值。在种群周期上升阶段于镭污染区捕获的苔原田鼠体内的226镭含量,肯定高于来自对照区的动物。已揭示出苔原田鼠不同性别 - 年龄组血液红细胞中脂质过氧化参数与体内226镭含量之间的相互关系。

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