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一例假性弹力纤维瘤病伴发缺血性跛行。

A case of pseudo-xanthoma elasticum presenting with ischaemic claudication.

机构信息

Department of Vascular Surgery, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK.

出版信息

Eur J Vasc Endovasc Surg. 2012 Apr;43(4):478-9. doi: 10.1016/j.ejvs.2012.01.001. Epub 2012 Jan 26.

Abstract

A 37-year-old man presented with symptoms of intermittent claudication. Investigations revealed atypical calf vessel disease but no obvious aetiology. Ten years later he re-presented with worsening symptoms. CT angiography confirmed the atypical pattern of lower limb arterial disease but also noted calcification of the renal parenchyma, myocardium and scrotum. A diagnosis of pseudo-xanthoma elasticum was confirmed by skin biopsy. Pseudo-xanthoma elasticum is a rare condition that presents infrequently to vascular surgeons. Early recognition should prompt aggressive risk factor management to slow accelerated atherosclerosis. Clinicians should be aware of the clinical features of this condition to allow early diagnosis.

摘要

一位 37 岁男性出现间歇性跛行症状。检查显示非典型小腿血管疾病,但无明显病因。十年后,他的症状恶化再次就诊。CT 血管造影证实了下肢动脉疾病的非典型模式,但也注意到肾脏实质、心肌和阴囊的钙化。皮肤活检证实了假性黄色瘤弹性组织病的诊断。假性黄色瘤弹性组织病是一种罕见疾病,很少向血管外科医生就诊。早期识别应促使积极管理危险因素以减缓动脉粥样硬化的加速进展。临床医生应了解该病症的临床特征,以便早期诊断。

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