Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
Neuron. 2012 Jan 26;73(2):207-9. doi: 10.1016/j.neuron.2012.01.002.
The adult mammalian central nervous system exhibits restricted regenerative potential. Chen et al. (2011) and El Bejjani and Hammarlund (2012) used Caenorhabditis elegans to uncover intrinsic factors that inhibit regeneration of axotomized mature neurons, opening avenues for potential therapeutics.
成年哺乳动物中枢神经系统的再生能力有限。Chen 等人(2011 年)和 El Bejjani 和 Hammarlund(2012 年)利用秀丽隐杆线虫揭示了抑制成熟神经元轴突切断后再生的内在因素,为潜在的治疗方法开辟了途径。