MOE Laboratory for Earth Surface Process, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China.
J Chromatogr A. 2012 Mar 2;1227:245-52. doi: 10.1016/j.chroma.2012.01.004. Epub 2012 Jan 11.
A sensitive liquid chromatography-electrospray tandem mass spectrometry method was established for the simultaneous determination of five monosubstituted polyfluoroalkyl phosphates (monoPAPs) and eight disubstituted polyfluoroalkyl phosphates (diPAPs) in drinking water. Complete separation and good retention for 13 polyfluoroalkyls phosphates (PAPs) were achieved with a Waters ACUITY UPLC BEH C8 column using a mixture of methanol/water containing 0.1% NH₄OH as the mobile phases. Extraction of drinking water samples was performed on weak anion exchange (WAX) cartridges, and the recoveries of target compounds were from 65 to 110%. The limits of quantization (LOQs) for 13 analytes were in the range of 0.4-40 ng/L. This method was applied to analyze the PAPs in drinking water samples from three cities in China. Of the 13 PAPs, six PAPs including 6:2 monoPAP (13.0 ng/L), 8:2 monoPAP (3.6 ng/L), 10:1 monoPAP (4.3-70.3 ng/L), 10:2 monoPAP (1.4-5.6 ng/L), 8:2 diPAP (0.10 ng/L), and 10:1 diPAP (0.8-3.8 ng/L) were detected.
建立了一种灵敏的液相色谱-电喷雾串联质谱法，用于同时测定饮用水中的 5 种单取代多氟烷基磷酸酯（monoPAPs）和 8 种双取代多氟烷基磷酸酯（diPAPs）。采用 Waters ACUITY UPLC BEH C8 柱，以甲醇/水混合溶液（含 0.1% NH₄OH）为流动相，可实现 13 种多氟烷基磷酸酯（PAPs）的完全分离和良好保留。采用弱阴离子交换（WAX）小柱提取饮用水样品，目标化合物的回收率为 65%110%。13 种分析物的定量限（LOQs）范围为 0.440ng/L。该方法应用于分析中国三个城市的饮用水中 PAPs 的含量。在 13 种 PAPs 中，检测到 6 种 PAPs，包括 6:2 monoPAP（13.0ng/L）、8:2 monoPAP（3.6ng/L）、10:1 monoPAP（4.3-70.3ng/L）、10:2 monoPAP（1.4-5.6ng/L）、8:2 diPAP（0.10ng/L）和 10:1 diPAP（0.8-3.8ng/L）。
