Veterinary Hospital, Federal University of Campina Grande, Patos, Paraíba, Brazil.
Res Vet Sci. 2012 Oct;93(2):811-2. doi: 10.1016/j.rvsc.2012.01.002. Epub 2012 Jan 27.
Primary amoebic meningoencephalitis is an acute disease of the central nervous system of humans and animals caused by Naegleria fowleri. This report describes a case of meningoencephalitis caused by N. fowleri in a crossbred, one-year-old bovine with progressive neurological signs. At necropsy there was thickening of the meninges and multifocal areas of malacia in the thalamus, caudal and rostral colliculi, parietal and occipital cortex, and cerebellum. Histologically there was multifocal necrosupurative meningoencephalitis associated with areas of malacia containing amoebic trophozoites. Immunohistochemistry of the brain was positive for N. fowleri. The disease should be included among the differential diagnosis of diseases of the central nervous system in cattle in areas where animals are exposed to hot, stagnant water.
原发性阿米巴脑膜脑炎是由福氏耐格里阿米巴引起的人类和动物中枢神经系统的急性疾病。本报告描述了一例由福氏耐格里阿米巴引起的脑膜脑炎，病牛为杂交品种，1 岁，具有进行性神经症状。剖检可见脑膜增厚，丘脑、尾状和头部视丘、顶叶和枕叶皮质以及小脑有多处软化区。组织学检查发现伴有多处坏死性化脓性脑膜脑炎，以及含有阿米巴滋养体的软化区。脑组织的免疫组织化学检查呈福氏耐格里阿米巴阳性。在动物暴露于热、停滞水的地区，应将该疾病纳入牛中枢神经系统疾病的鉴别诊断中。
