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[轴向和外周型脊柱关节炎的磁共振成像检查]

[MRI examinations for axial and peripheral spondyloarthritis].

作者信息

Baraliakos X, Braun J

机构信息

Rheumazentrum Ruhrgebiet Herne, Ruhr Universität Bochum, Landgrafenstr. 15, 44652, Herne, Deutschland.

出版信息

Z Rheumatol. 2012 Jan;71(1):27-37. doi: 10.1007/s00393-011-0894-3.

DOI:10.1007/s00393-011-0894-3
PMID:22286353
Abstract

The diagnosis of ankylosing spondylitis (AS) is based on the modified New York criteria and therefore on defined structural changes in the sacroiliac joint as detected by conventional radiographs. However, x-rays are not able to detect early stages of the disease in which inflammation predominates and irreversible structural changes have not yet taken place. This probably contributes to a substantial time delay until a diagnosis is made. Magnetic resonance imaging (MRI) is able to visualize active and chronic changes in axial and peripheral spondyloarthritis (SpA) even before the occurrence of structural changes. The ability to demonstrate both active and, in a limited way, also structural changes makes MRI a diagnostic tool of increasing importance in the management of SpA. However, conventional radiographs are still the gold standard for the assessment of structural changes in SpA. A combination of both imaging techniques is recommended in clinical practice.

摘要

强直性脊柱炎(AS)的诊断基于改良的纽约标准,因此基于传统X线片检测到的骶髂关节明确的结构变化。然而,X线无法检测到疾病的早期阶段,此时炎症为主且尚未发生不可逆的结构变化。这可能导致诊断出现相当长的时间延迟。磁共振成像(MRI)甚至在结构变化出现之前就能显示轴性和外周脊柱关节炎(SpA)的活动期和慢性期变化。能够显示活动期变化以及在一定程度上显示结构变化,使得MRI成为SpA管理中越来越重要的诊断工具。然而,传统X线片仍是评估SpA结构变化的金标准。临床实践中建议将这两种成像技术结合使用。

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RMD Open. 2017 Apr 24;3(1):e000430. doi: 10.1136/rmdopen-2017-000430. eCollection 2017.

本文引用的文献

1
Descriptions of spinal MRI lesions and definition of a positive MRI of the spine in axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI study group.轴向型脊柱关节炎脊柱 MRI 病变描述和脊柱 MRI 阳性定义:ASAS/OMERACT MRI 研究组的共识方法。
Ann Rheum Dis. 2012 Aug;71(8):1278-88. doi: 10.1136/ard.2011.150680. Epub 2012 May 14.
2
MRI inflammation at the vertebral unit only marginally predicts new syndesmophyte formation: a multilevel analysis in patients with ankylosing spondylitis.仅在椎体单元的 MRI 炎症程度对新的联合骨赘形成有轻微预测作用:强直性脊柱炎患者的多水平分析。
Ann Rheum Dis. 2012 Mar;71(3):369-73. doi: 10.1136/annrheumdis-2011-200208. Epub 2011 Oct 6.
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Identifying patients with axial spondyloarthritis in primary care: how useful are items indicative of inflammatory back pain?
在基层医疗中识别中轴型脊柱关节炎患者:提示炎症性背痛的项目有多大用处?
Ann Rheum Dis. 2011 Oct;70(10):1782-7. doi: 10.1136/ard.2011.151167. Epub 2011 Aug 5.
4
2010 Update of the international ASAS recommendations for the use of anti-TNF agents in patients with axial spondyloarthritis.2010 年强直性脊柱炎评估与治疗方法国际协会(ASAS)关于抗 TNF 药物治疗中轴型脊柱关节炎的推荐更新。
Ann Rheum Dis. 2011 Jun;70(6):905-8. doi: 10.1136/ard.2011.151563.
5
Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.强直性脊柱炎疾病活动评分 (ASDAS):确定疾病活动状态和改善评分的临界值。
Ann Rheum Dis. 2011 Jan;70(1):47-53. doi: 10.1136/ard.2010.138594. Epub 2010 Nov 10.
6
Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis.Dickkopf-1(Dkk-1)在强直性脊柱炎中功能失调的证据。
Arthritis Rheum. 2010 Jan;62(1):150-8. doi: 10.1002/art.27231.
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Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis.硬化蛋白在强直性脊柱炎中的骨骼表达改变及其与影像学进展的关联。
Arthritis Rheum. 2009 Nov;60(11):3257-62. doi: 10.1002/art.24888.
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Magnetic resonance imaging assessment of spinal inflammation in ankylosing spondylitis: standard clinical protocols may omit inflammatory lesions in thoracic vertebrae.强直性脊柱炎脊柱炎症的磁共振成像评估:标准临床方案可能会遗漏胸椎的炎性病变。
Arthritis Rheum. 2009 Sep 15;61(9):1187-93. doi: 10.1002/art.24561.
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Clinical and imaging efficacy of infliximab in HLA-B27-Positive patients with magnetic resonance imaging-determined early sacroiliitis.英夫利昔单抗在磁共振成像确诊的早期骶髂关节炎HLA - B27阳性患者中的临床及影像疗效
Arthritis Rheum. 2009 Apr;60(4):946-54. doi: 10.1002/art.24408.