Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Magn Reson Med. 2012 Nov;68(5):1527-35. doi: 10.1002/mrm.24163. Epub 2012 Jan 27.
Wideband steady-state free precession (WB-SSFP) is a modification of balanced steady-state free precession utilizing alternating repetition times to reduce susceptibility-induced balanced steady-state free precession limitations, allowing its use for high-resolution myelographic-contrast spinal imaging. Intertissue contrast and spatial resolution of complete-spine-coverage 3D WB-SSFP were compared with those of 2D T₂-weighted fast spin echo, currently the standard for spine T₂-imaging. Six normal subjects were imaged at 1.5 and 3 T. The signal-to-noise ratio efficiency (SNR per unit-time and unit-volume) of several tissues was measured, along with four intertissue contrast-to-noise ratios; nerve-ganglia:fat, intradural-nerves:cerebrospinal fluid, nerve-ganglia:muscle, and muscle:fat. Patients with degenerative and traumatic spine disorders were imaged at both MRI fields to demonstrate WB-SSFP clinical advantages and disadvantages. At 3 T, WB-SSFP provided spinal contrast-to-noise ratios 3.7-5.2 times that of fast spin echo. At 1.5 T, WB-SSFP contrast-to-noise ratio was 3-3.5 times that of fast spin echo, excluding a 1.7 ratio for intradural-nerves:cerebrospinal fluid. WB-SSFP signal-to-noise ratio efficiency was also higher. Three-dimensional WB-SSFP disadvantages relative to 2D fast spin echo are reduced edema hyperintensity, reduced muscle signal, and higher motion sensitivity. WB-SSFP's high resolution and contrast-to-noise ratio improved visualization of intradural nerve bundles, foraminal nerve roots, and extradural nerve bundles, improving detection of nerve compression in radiculopathy and spinal-stenosis. WB-SSFP's high resolution permitted reformatting into orthogonal planes, providing distinct advantages in gauging fine spine pathology.
宽带稳态自由进动(WB-SSFP)是一种改良的平衡稳态自由进动技术,利用交替重复时间来降低磁化率引起的平衡稳态自由进动限制,使其可用于高分辨率脊髓造影磁共振成像。本文比较了完整脊柱覆盖三维 WB-SSFP 与二维 T₂加权快速自旋回波(目前是脊柱 T₂成像的标准)的组织对比度和空间分辨率。在 1.5T 和 3T 对 6 名正常受试者进行了成像。测量了几种组织的信噪比效率(单位时间和单位体积的 SNR),以及 4 种组织对比度噪声比:神经节:脂肪、硬脊膜内神经:脑脊液、神经节:肌肉和肌肉:脂肪。对患有退行性和外伤性脊柱疾病的患者进行了两种 MRI 场的成像,以展示 WB-SSFP 的临床优缺点。在 3T 时,WB-SSFP 提供的脊髓对比度噪声比是快速自旋回波的 3.7-5.2 倍。在 1.5T 时,WB-SSFP 的对比度噪声比是快速自旋回波的 3-3.5 倍,不包括硬脊膜内神经:脑脊液的 1.7 倍。WB-SSFP 的信噪比效率也更高。与 2D 快速自旋回波相比,3D WB-SSFP 的缺点是水肿高信号减少、肌肉信号减少和运动敏感性增加。WB-SSFP 的高分辨率和对比度噪声比改善了硬膜内神经束、椎间孔神经根和硬膜外神经束的可视化,提高了对神经根病和脊柱狭窄症中神经压迫的检测能力。WB-SSFP 的高分辨率允许重新格式化为正交平面,在评估精细脊柱病变方面具有明显优势。