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使用支持向量机分类器自动识别阻塞性睡眠呼吸暂停综合征。

Automated recognition of obstructive sleep apnea syndrome using support vector machine classifier.

作者信息

Al-Angari Haitham M, Sahakian Alan V

机构信息

Department of Electrical Engineering and Computer Science, Northwestern University, Evanston, IL 60208, USA.

出版信息

IEEE Trans Inf Technol Biomed. 2012 May;16(3):463-8. doi: 10.1109/TITB.2012.2185809. Epub 2012 Jan 24.

Abstract

Obstructive sleep apnea (OSA) is a common sleep disorder that causes pauses of breathing due to repetitive obstruction of the upper airways of the respiratory system. The effect of this phenomenon can be observed in other physiological signals like the heart rate variability, oxygen saturation, and the respiratory effort signals. In this study, features from these signals were extracted from 50 control and 50 OSA patients from the Sleep Heart Health Study database and implemented for minute and subject classifications. A support vector machine (SVM) classifier was used with linear and second-order polynomial kernels. For the minute classification, the respiratory features had the highest sensitivity while the oxygen saturation gave the highest specificity. The polynomial kernel always had better performance and the highest accuracy of 82.4% (Sen: 69.9%, Spec: 91.4%) was achieved using the combined-feature classifier. For subject classification, the polynomial kernel had a clear improvement in the oxygen saturation accuracy as the highest accuracy of 95% was achieved by both the oxygen saturation (Sen: 100%, Spec: 90.2%) and the combined-feature (Sen: 91.8%, Spec: 98.0%). Further analysis of the SVM with other kernel types might be useful for optimizing the classifier with the appropriate features for an OSA automated detection algorithm.

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见的睡眠障碍,由于呼吸系统上呼吸道的反复阻塞导致呼吸暂停。这种现象的影响可以在其他生理信号中观察到,如心率变异性、血氧饱和度和呼吸努力信号。在本研究中,从睡眠心脏健康研究数据库的50名对照者和50名OSA患者中提取了这些信号的特征,并用于分钟和个体分类。使用支持向量机(SVM)分类器,采用线性和二阶多项式核。对于分钟分类,呼吸特征的敏感性最高,而血氧饱和度的特异性最高。多项式核总是具有更好的性能,使用组合特征分类器时达到了最高准确率82.4%(敏感性:69.9%,特异性:91.4%)。对于个体分类,多项式核在血氧饱和度准确率方面有明显提高,血氧饱和度(敏感性:100%,特异性:90.2%)和组合特征(敏感性:91.8%,特异性:98.0%)均达到了最高准确率95%。使用其他核类型对SVM进行进一步分析,可能有助于使用适合OSA自动检测算法的特征来优化分类器。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ce/4487628/c5988d380984/nihms-701756-f0001.jpg

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