Wittkowski W, Bergmann M, Hoffmann K, Pera F
Institute of Anatomy, University of Münster, Federal Republic of Germany.
Cell Tissue Res. 1988 Jan;251(1):183-7. doi: 10.1007/BF00215463.
Certain secretory cells in the hypophysial pars tuberalis of the Djungarian hamster display marked circannual structural alterations. The present investigation deals with the immunohistochemical properties of this cell group. A distinct TSH-like immunoreactivity was found in secretory cells of this type in the pars tuberalis of animals exposed to long photoperiods, whereas under short photoperiods the TSH-like immunoreactivity was nearly absent. In the pars distalis, the number and distribution of TSH-positive cells did not differ significantly between animals maintained under long and under short photoperiods. LH- and FSH-positive cells could not be detected in the pars tuberalis, but they are clearly present in the pars distalis of both groups of hamsters. Our immunocytochemical results suggest that photoperiodic stimuli influence the secretory activity of TSH-like immunoreactive cells in the pars tuberalis. A connection with the neuroendrocrine-thyroid axis is discussed.
布氏田鼠垂体结节部的某些分泌细胞呈现出明显的年周期结构变化。本研究探讨了该细胞群的免疫组化特性。在暴露于长光照周期的动物的结节部，这类分泌细胞中发现了明显的促甲状腺激素（TSH）样免疫反应性，而在短光照周期下，TSH样免疫反应性几乎不存在。在远侧部，长光照周期和短光照周期饲养的动物之间，TSH阳性细胞的数量和分布没有显著差异。在结节部未检测到促黄体生成素（LH）和促卵泡生成素（FSH）阳性细胞，但在两组仓鼠的远侧部均明显存在。我们的免疫细胞化学结果表明，光照周期刺激会影响结节部TSH样免疫反应性细胞的分泌活动。本文还讨论了与神经内分泌-甲状腺轴的联系。
