Won Andy C M, Ethell Anthony
St George Hospital, Kogarah, NSW 2217, Australia.
Int J Surg Case Rep. 2012;3(3):97-9. doi: 10.1016/j.ijscr.2011.08.012. Epub 2011 Oct 1.
Infectious mononucleosis is common among young adults and teenagers. However, spontaneous rupture of spleen secondary to IM is rare and it is the most frequent cause of death in infectious mononucleosis.
A previously healthy 16-year-old girl presented with a one-week history of sore throat, non-productive cough, fever, malaise and a positive Monospot test. Prior to transfer to the hospital, she had two syncopal episodes and a complaint of abdominal pain at home. Clinical examination revealed that she was febrile and mildly tachycardic with an evidence of localised peritonism on her left upper quadrant. Urgent abdominal ultrasound and computed tomography scan showed subcapsular haematoma with a significant amount of complex fluid within the abdominal cavity, especially the left flank. Emergency laparotomy was performed and a moderate amount of haemoperitoneum was evacuated. The spleen was found grossly enlarged with a haematoma identified on the ruptured capsule. Splenectomy was performed and peritoneal cavity was washed out meticulously prior to the closure of the abdominal wall.
Despite the fact that infectious mononucleosis is a self-limiting disease, it may cause serious and lethal complications. The best treatment of splenic rupture secondary to infectious mononucleosis has been controversial but it is mainly based on the haemodynamical status of the patient and the experience of the treating surgeon.
Spontaneous rupture of spleen secondary to IM can be lethal in those patients with high possibility of deterioration with conservative management, thus timely surgical intervention is required.
传染性单核细胞增多症在年轻成年人和青少年中很常见。然而,传染性单核细胞增多症继发的脾脏自发性破裂很少见,却是传染性单核细胞增多症最常见的死亡原因。
一名既往健康的16岁女孩,有一周的咽痛、干咳、发热、乏力病史,嗜异性凝集试验呈阳性。在转院之前,她在家中发生了两次晕厥发作并主诉腹痛。临床检查发现她发热,轻度心动过速,左上腹有局限性腹膜炎体征。紧急腹部超声和计算机断层扫描显示脾包膜下血肿,腹腔内,尤其是左侧腹有大量复杂液体。进行了急诊剖腹手术,排出了中等量的腹腔积血。发现脾脏明显肿大,破裂包膜上有血肿。进行了脾切除术,在关闭腹壁之前仔细冲洗了腹腔。
尽管传染性单核细胞增多症是一种自限性疾病,但它可能导致严重和致命的并发症。传染性单核细胞增多症继发脾破裂的最佳治疗方法一直存在争议,但主要基于患者的血流动力学状态和主治外科医生的经验。
传染性单核细胞增多症继发的脾脏自发性破裂对于那些保守治疗很可能病情恶化的患者可能是致命的,因此需要及时进行手术干预。