Borowitz M J
School of Medicine, Duke University, Durham, North Carolina.
Hematol Oncol Clin North Am. 1990 Aug;4(4):743-65.
This article details the immunologic diversity of acute lymphoblastic leukemia in children. A historical review of developments in immunophenotyping is followed by a discussion of how major subgroups of leukemia are best defined today. The relationship of immunologic subtypes to stages of normal lymphoid development is explored, and the clinical impact of immunophenotyping is discussed.
本文详细介绍了儿童急性淋巴细胞白血病的免疫多样性。在对免疫表型分析发展的历史回顾之后，讨论了如今如何最好地定义白血病的主要亚组。探讨了免疫亚型与正常淋巴发育阶段的关系，并讨论了免疫表型分析的临床影响。
