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干细胞在眼部神经退行性变中的新兴作用:炒作还是希望?

The emerging role of stem cells in ocular neurodegeneration: hype or hope?

机构信息

Department of Neurology, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh 160012, India.

出版信息

Mol Cell Biochem. 2012 Jun;365(1-2):65-76. doi: 10.1007/s11010-012-1244-8.

Abstract

Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness. Thus, an appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these diseases. In this review, we provide an overview of retinal disorders in the context of biotherapeutic approaches in these disorders.

摘要

影响全球超过一亿人,视网膜疾病是导致不可逆性视力损害和失明的主要原因之一。因此,适当的研究模型,特别是动物模型,对于深入了解这些疾病的病因、病理和进展至关重要。在这篇综述中,我们提供了在这些疾病的生物治疗方法的背景下对视网膜疾病的概述。

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