生长与发育：为生长激素缺乏的女性研发更好的药物 - Suppr

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Growth and development: patching up a better pill for GH-deficient women.

作者信息

Birzniece Vita, Ho Ken K Y

出版信息

Nat Rev Endocrinol. 2012 Jan 31;8(4):197-8. doi: 10.1038/nrendo.2012.9.

DOI:10.1038/nrendo.2012.9

PMID:22290355

Abstract

摘要

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Differential effects of raloxifene and estrogen on body composition in growth hormone-replaced hypopituitary women.雷洛昔芬和雌激素对生长激素替代治疗的垂体功能减退妇女身体成分的影响。

J Clin Endocrinol Metab. 2012 Mar;97(3):1005-12. doi: 10.1210/jc.2011-2837. Epub 2011 Dec 14.

Effects of oral and transdermal estrogen on IGF1, IGFBP3, IGFBP1, serum lipids, and glucose in patients with hypopituitarism during GH treatment: a randomized study.口服和透皮雌激素对生长激素治疗垂体功能减退症患者 IGF1、IGFBP3、IGFBP1、血脂和血糖的影响：一项随机研究。

Eur J Endocrinol. 2012 Feb;166(2):207-13. doi: 10.1530/EJE-11-0560. Epub 2011 Nov 22.

Quantification of the adverse effect of ethinylestradiol containing oral contraceptive pills when used in conjunction with growth hormone replacement in routine practice.在常规实践中，结合生长激素替代疗法使用含炔雌醇的口服避孕药的不良影响的量化。

Clin Endocrinol (Oxf). 2012 May;76(5):729-33. doi: 10.1111/j.1365-2265.2011.04277.x.

Estrogen replacement in women of fertile years with hypopituitarism.

J Clin Endocrinol Metab. 2005 Nov;90(11):5964-9. doi: 10.1210/jc.2005-1207. Epub 2005 Aug 9.

Comparison of the metabolic effects of raloxifene and oral estrogen in postmenopausal and growth hormone-deficient women.雷洛昔芬与口服雌激素对绝经后及生长激素缺乏女性代谢影响的比较。

J Clin Endocrinol Metab. 2005 Jul;90(7):3897-903. doi: 10.1210/jc.2005-0173. Epub 2005 Apr 26.

Estrogen regulation of growth hormone action.雌激素对生长激素作用的调节。

Endocr Rev. 2004 Oct;25(5):693-721. doi: 10.1210/er.2003-0035.

Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women.口服雌激素可拮抗生长激素缺乏女性体内生长激素的代谢作用。

Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1191-6. doi: 10.1152/ajpendo.2001.281.6.E1191.

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Biologic effects of transdermal estradiol.经皮雌二醇的生物学效应。

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