Department of Urology, Vrije Universiteit Brussel (VUB), Belgium.
Arch Med Sci. 2011 Oct;7(5):858-63. doi: 10.5114/aoms.2011.25562. Epub 2011 Nov 8.
The aim of study is comparing the haemostatic properties of conventional monopolar resection (TURP) and bipolar transurethral resection in saline (TURIS) of the prostate in patients under chronic oral anticoagulants.
Out of a cohort group of 550 endoscopic resections for bladder outlet obstruction, 176 patients on chronic oral anticoagulant therapy required endoscopic resection either by monopolar TURP or bipolar TURIS technology. Changes in haemoglobin, blood transfusion, and clot retention were compared between both groups.
Mean postoperative change in haemoglobin level was -1.21 ±0.92 mg/dl in the TURP group compared to -1.29 ±0.99 mg/dl in the TURIS group (p = 0.603). The need for blood transfusions and the mean numbers of units transfused did not significantly differ between the 2 groups. Clot retention appeared in 12 patients (15%) in the TURP group compared to 13 patients (13%) in the TURIS group (p = 0.828).
Despite promising experimental results of better haemostasis and deeper coagulation depth, bipolar technology does not permit one to reduce the amount of blood loss when compared to patients treated by conventional monopolar technology in this study group of patients on oral anticoagulation therapy. Patients on oral anticoagulants suffer more incidents of clot retention, which sometimes results in re-hospitalisation.
本研究旨在比较慢性口服抗凝治疗患者中传统单极前列腺切除术(TURP)和双极经尿道前列腺切除术(TURIS)的止血特性。
在 550 例因膀胱出口梗阻而行内镜切除术的患者中,有 176 例接受慢性口服抗凝治疗的患者需要行内镜切除术,分别采用单极 TURP 或双极 TURIS 技术。比较两组患者的血红蛋白变化、输血和血凝块保留情况。
TURP 组术后平均血红蛋白水平变化为-1.21±0.92mg/dl,TURIS 组为-1.29±0.99mg/dl(p=0.603)。两组间输血需求和平均输血量无显著差异。TURP 组有 12 例(15%)患者出现血凝块保留,TURIS 组有 13 例(13%)患者出现血凝块保留(p=0.828)。
尽管双极技术在实验中具有更好的止血和更深的凝血深度的前景,但与本研究组接受传统单极技术治疗的口服抗凝治疗患者相比,该技术并未减少出血量。接受口服抗凝治疗的患者血凝块保留的发生率更高,有时会导致再次住院。