Kantar Health, New York , NY, 10010, USA.
COPD. 2012 Feb;9(1):46-57. doi: 10.3109/15412555.2011.634863.
Abstract To address the gap in knowledge about the impact of chronic obstructive pulmonary disease (COPD) on older working adults, this study examined quality of life, worker productivity, and healthcare resource utilization among employed adults aged 65 and older with and without COPD. Among 2009 National Health and Wellness Survey (a cross-sectional, internet-based survey representative of the US adult population) respondents, employed adults aged 65 years and older, with COPD (n = 297) and without COPD (n = 3061), were included in analyses. Impact of self-reported COPD diagnosis on mean quality of life (using health utilities and mental, MCS, and physical, PCS, component summary scores from SF-12v2), work productivity and activity impairment (using the WPAI questionnaire), and resource use were examined. Adjusting for demographic and health characteristics such as co-morbidities (weighted to project to the US population) in regression models (linear, negative binomial, or logistic, as appropriate given the outcome measure), older workers with COPD reported significantly lower MCS (52.1 vs. 53.4, p < .05), PCS (40.3 vs. 47.2, p < .05), and health utilities (0.72 vs. 0.79, p < .05) than those without COPD, and significantly greater percentages of impairment while at work (presenteeism) (12.6% vs. 8.7%, p < .0001), overall work impairment (absenteeism and presenteeism combined) (19.3% vs. 10.0%, p < .05), and impairment in daily activities (23.9% vs. 13.7%, p < .05). There were no significant differences in absenteeism or healthcare use. Quality of life and work productivity suffered among employed adults aged 65 years and older with COPD, emphasizing the need for disease management in this population.
摘要 为了弥补关于慢性阻塞性肺疾病（COPD）对老年在职成年人影响的知识空白，本研究调查了患有和不患有 COPD 的 65 岁及以上在职成年人的生活质量、工人生产力和医疗资源利用情况。在 2009 年全国健康和健康调查（一项基于互联网的、代表美国成年人口的横断面调查）中，65 岁及以上的在职成年人，包括患有 COPD（n=297）和不患有 COPD（n=3061）的成年人，都被纳入了分析。调查了自我报告的 COPD 诊断对平均生活质量（使用健康效用和心理 MCS 和身体 PCS 成分综合评分从 SF-12v2）、工作生产力和活动障碍（使用 WPAI 问卷）以及资源使用的影响。在回归模型中（根据结果衡量标准，适当使用线性、负二项式或逻辑回归），调整了包括合并症在内的人口统计学和健康特征（加权以预测美国人口），患有 COPD 的老年工人报告的 MCS（52.1 比 53.4，p<.05）、PCS（40.3 比 47.2，p<.05）和健康效用（0.72 比 0.79，p<.05）明显低于没有 COPD 的工人，而在工作时的障碍（出勤）（12.6%比 8.7%，p<.0001）、总体工作障碍（缺勤和出勤）（19.3%比 10.0%，p<.05）和日常活动障碍（23.9%比 13.7%，p<.05）的百分比明显更高。缺勤或医疗保健使用没有显著差异。患有 COPD 的 65 岁及以上在职成年人的生活质量和工作生产力下降，这强调了在这一人群中进行疾病管理的必要性。
