Takahashi K, Lai L C, Ghatei M A, James V H, Bloom S R
Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
J Clin Endocrinol Metab. 1990 Dec;71(6):1681-3. doi: 10.1210/jcem-71-6-1681.
Immunoreactive endothelin has been detected in 21 of 43 samples of breast cyst fluid (21 cases; 3.5 +/- 0.6 pmol/l, mean +/- SEM. Other 22 cases; not detectable, less than 0.5 pmol/l). Fast protein liquid chromatographic analysis of the immunoreactive endothelin of pooled breast cyst fluid showed two immunoreactive peaks; one in the void volume and the other in the position of endothelin-1. It is probable that endothelin-1 is produced by the epithelial cells lining breast cysts, but significance of the presence of endothelin-1 in breast cyst fluid remains to be elucidated.
在43份乳腺囊肿液样本中的21份检测到免疫反应性内皮素（21例；3.5±0.6皮摩尔/升，平均值±标准误。其他22例未检测到，低于0.5皮摩尔/升）。对合并的乳腺囊肿液免疫反应性内皮素进行快速蛋白质液相色谱分析显示有两个免疫反应峰；一个在空体积位置，另一个在内皮素-1的位置。内皮素-1很可能由乳腺囊肿内衬的上皮细胞产生，但乳腺囊肿液中内皮素-1存在的意义仍有待阐明。
