Chitrathara K, Sheikh Z A, Vijaykumar D K, Kuriakose S, Anupama R, Nandeesh M
Department of Surgical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Indian J Cancer. 2011 Oct-Dec;48(4):471-6. doi: 10.4103/0019-509X.92259.
Hysterectomy is an integral part of ovarian cancer surgery. The authors have evaluated the uterine involvement in ovarian cancer in this study.
Conventionally, removal of the uterus is considered an essential part of ovarian cancer surgery, but rationale for same in absence of its gross involvement is questionable. Aim of this study was to evaluate the microscopic involvement of uterus in ovarian cancer and whether there are any predictors of uterine involvement.
Retrospective study.
The authors analyzed 128 patients of epithelial ovarian cancer (EOC) operated from 2004 January to 2008 June, who had not undergone hysterectomy previously. Data regarding their demographic, clinical, and pathological findings was collected and analyzed.
Chi-square test.
Most of our patients (n=111) presented with stage III or above. Serous carcinoma was the most common histology encountered (86.7%). Uterus was grossly involved in only 19 patients and microscopic involvement was noted in 20 patients. Only one patient with absence of gross involvement had microscopic disease in the uterus. Involvement of the uterus was found to be independent of stage, type of tumor, laterality, and preoperative chemotherapy. The grade of tumor and gross uterine involvement were only factors that showed statistically significant correlation with microscopic uterine involvement. Only one patient had synchronous endometrial cancer.
Uterine involvement in EOC is not common. Absence of gross uterine involvement reliably predicts absence of microscopic disease.
子宫切除术是卵巢癌手术的一个重要组成部分。在本研究中，作者评估了卵巢癌中子宫的受累情况。
传统上，子宫切除被认为是卵巢癌手术的一个必要部分，但在子宫无肉眼可见受累的情况下这样做的合理性值得怀疑。本研究的目的是评估卵巢癌中子宫的微观受累情况以及是否存在子宫受累的预测因素。
回顾性研究。
作者分析了2004年1月至2008年6月期间接受手术的128例上皮性卵巢癌（EOC）患者，这些患者之前未接受过子宫切除术。收集并分析了有关其人口统计学、临床和病理结果的数据。
卡方检验。
我们的大多数患者（n = 111）表现为III期或以上。浆液性癌是最常见的组织学类型（86.7%）。仅19例患者子宫有肉眼可见受累，20例患者有微观受累。仅1例无肉眼可见受累的患者子宫有微观病变。发现子宫受累与分期、肿瘤类型、侧别和术前化疗无关。肿瘤分级和子宫肉眼受累是仅有的与子宫微观受累有统计学显著相关性的因素。仅1例患者有同步性子宫内膜癌。
EOC中子宫受累并不常见。子宫无肉眼可见受累可可靠地预测无微观病变。
