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股四头肌无力是否是膝关节骨关节炎发生或进展的危险因素?

Is quadriceps muscle weakness a risk factor for incident or progressive knee osteoarthritis?

机构信息

Department of Orthopaedics and Rehabilitation, Iowa City, IA, USA.

出版信息

Phys Sportsmed. 2011 Nov;39(4):44-50. doi: 10.3810/psm.2011.11.1938.

DOI:10.3810/psm.2011.11.1938
PMID:22293767
Abstract

The role of the quadriceps muscle in mediating risk for knee osteoarthritis (OA) is a common subject of investigation. The quadriceps muscle is a principal contributor to knee joint stability and provides shock absorption for the knee during ambulation. Clinically, weakness of the quadriceps muscle is consistently found in patients with knee OA. Research has shown that higher quadriceps muscle strength is associated with a reduced risk for incident symptomatic knee OA. However, there is limited evidence to suggest that quadriceps muscle plays a significant role in the incidence of radiographic knee OA. In addition, greater quadriceps muscle strength is associated with a lower risk for progression of tibiofemoral joint space narrowing and cartilage loss in women. This article summarizes knowledge of the relationship between quadriceps muscle strength and risk for knee OA.

摘要

股四头肌在介导膝关节骨关节炎(OA)风险中的作用是一个常见的研究课题。股四头肌是膝关节稳定性的主要贡献者,在步行时为膝关节提供减震。临床上,膝关节 OA 患者常伴有股四头肌无力。研究表明,股四头肌力量越高,患症状性膝关节 OA 的风险越低。然而,有有限的证据表明股四头肌在放射学膝关节 OA 的发病中起重要作用。此外,股四头肌力量越大,女性胫股关节间隙变窄和软骨丢失的进展风险越低。本文总结了股四头肌力量与膝关节 OA 风险之间关系的知识。

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