Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA.
Phys Sportsmed. 2011 Nov;39(4):60-9. doi: 10.3810/psm.2011.11.1940.
Osteochondral lesions of the knee is a common disorder in adolescents, although it may present in children and adults. Despite the fact that the disorder was discovered more than a century ago, no specific causes have been identified, although relationships with ischemia, irregular ossification of epiphyseal cartilage, genetic influences, trauma, and endocrine disorders have been postulated. Taking a thorough history and performing a thorough physical examination will facilitate diagnosis of this condition. Radiographic and magnetic resonance imaging are useful diagnostic tools that aid in the evaluation. A comprehensive knowledge of the relevant anatomy and clinical progression of osteochondral lesions allows for a better understanding of the classification systems and, ultimately management of this disorder. The size, location, and stability of the lesion, as well as the patient's age, are crucial in determining optimal treatment. The spectrum of injury ranges from small, stable lesions, which can be treated nonoperatively, to unstable or displaced lesions, which may require surgical management. Surgical options include drilling of subchondral bone, curettage and microfracture, refixation of detached lesions, autologous osteochondral autograft procedures (eg, mosaicplasty, osteochondral autograft transfer system), autologous chondrocyte implantation, and osteochondral allograft resurfacing. This article provides a basic approach to the evaluation and management of osteochondral lesions, as well as indications for surgery.
膝关节骨软骨病损是青少年的一种常见疾病,尽管也可发生于儿童和成年人。尽管该疾病在一个多世纪前就已被发现,但仍未明确其具体病因,尽管有人提出与缺血、骺软骨不规则骨化、遗传影响、创伤和内分泌紊乱有关。详细的病史采集和全面的体格检查有助于诊断这种疾病。影像学和磁共振成像(MRI)是有用的诊断工具,有助于评估。全面了解骨软骨病损的相关解剖结构和临床进展有助于更好地理解分类系统,最终有助于这种疾病的治疗。病损的大小、位置和稳定性,以及患者的年龄,对于确定最佳治疗方案至关重要。损伤的范围从可以非手术治疗的小而稳定的病损到不稳定或移位的病损不等,后者可能需要手术治疗。手术选择包括软骨下骨钻孔、刮除和微骨折、游离病损的再固定、自体骨软骨移植术(如马赛克plasty、自体软骨移植转移系统)、自体软骨细胞移植和骨软骨同种异体移植表面置换。本文提供了一种评估和管理骨软骨病损的基本方法,以及手术适应证。