Department of Ophthalmology, University Hospital No 5, Medical University of Silesia, Katowice, Poland.
Med Sci Monit. 2012 Feb;18(2):CR51-57. doi: 10.12659/msm.882455.
Central serous chorioretinopathy (CSC) is a condition that originates from alterations of the choroidal circulation. The aim of this paper was to evaluate the use of indocyanine green angiography (ICGA) in patients with chronic CSC.
MATERIAL/METHODS: The analysis included 17 patients (34 eyes) with chronic CSC in at least 1 eye. The eye examination included: distance and near visual acuity, biomicroscopy, applanation tonometry, fundus examination, colored and red-free fundus photography, evaluation of autofluorescence, optical coherence tomography, and fluorescein and indocyanine green angiography.
In 34 eyes (100%) involved in the ICGA study the results revealed zones of transient increased choroidal vessels permeability. In 18 eyes (52.9%) choroidal changes were accompanied by a focal serous pigment epithelial detachment. In 4 eyes (11.8%) of 3 patients' the ICGA examination confirmed the presence of occult choroidal neovascularization (CNV). In the patient with bilateral diffuse retinal pigment epitheliopathy, CNV was present in 1 eye, in the patient with unilateral chronic CSC it was also present in 1 eye, and in the third patient with bilateral chronic CSC it was detected in both eyes.
ICGA is a very useful examination that enables ophthalmologists to visualize choroidal changes due to chronic CSC, as well as to diagnose occult CNV in chronic CSC.
中心性浆液性脉络膜视网膜病变（CSC）是一种起源于脉络膜循环改变的疾病。本文旨在评估吲哚菁绿血管造影（ICGA）在慢性 CSC 患者中的应用。
材料/方法：分析包括 17 例（34 只眼）至少一眼患有慢性 CSC 的患者。眼部检查包括：远、近视力、眼前节检查、眼压测量、眼底检查、彩色眼底照相和自发荧光检查、光学相干断层扫描（OCT）以及荧光素和吲哚菁绿血管造影。
在 34 只眼（100%）的 ICGA 研究中，结果显示出短暂的脉络膜血管通透性增加区域。在 18 只眼（52.9%）中，脉络膜变化伴有局灶性浆液性色素上皮脱离。在 3 例 4 只眼（11.8%）中，ICGA 检查证实存在隐匿性脉络膜新生血管（CNV）。在双侧弥漫性视网膜色素上皮病变的患者中，CNV 存在于 1 只眼中，在单侧慢性 CSC 的患者中也存在于 1 只眼中，在双侧慢性 CSC 的第三位患者中，在 2 只眼中均检测到 CNV。
ICGA 是一种非常有用的检查方法，使眼科医生能够观察到慢性 CSC 引起的脉络膜变化，并诊断慢性 CSC 中的隐匿性 CNV。
