Sahoo Niroj Kumar, Singh Sumit Randhir, Beale Oliver, Nkrumah Gideon, Rasheed Mohammed Abdul, Jabeen Asiya, Vupparaboina Kiran Kumar, Ibrahim Mohammed Nasar, Tatti Filippo, Chandra Khushboo, Lanza Michele, Iovino Claudio, Peiretti Enrico, Chhablani Jay
Department of Retina and Vitreous, L V Prasad Eye Institute, Vijayawada 521134, India.
Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, San Diego, CA 92697, USA.
Diagnostics (Basel). 2021 May 11;11(5):861. doi: 10.3390/diagnostics11050861.
To map the choroidal vascularity index and compare two eyes in patients with unilateral central serous chorioretinopathy (CSCR).
This was a retrospective, observational study performed in patients with unilateral CSCR. Choroidal thickness (CT) and Choroidal vascularity index (CVI) were measured and mapped in various zones according to the early treatment diabetic retinopathy (ETDRS) grid.
A total of 20 CSCR patients (20 study and 20 fellow eyes) were included in the study. Outer nasal region CT was seen to be significantly lower than central CT ( = 0.042) and inner nasal CT ( = 0.007); outer ring CT was significantly less than central ( = 0.04) and inner ring ( = 0.01) CT in CSCR eyes. On potting all the CVI values against the corresponding CT values, a positive correlation was seen in CSCR eyes ( = 0.54, < 0.01), which was slightly weaker in fellow eyes ( = 0.3, < 0.01) and a negative correlation was seen in healthy eyes ( = -0.262, < 0.01).
Correlation between CVI and CT was altered in CSCR eyes as compared to fellow and normal eyes with increasing CVI towards the center of the macula and superiorly in CSCR eyes.
绘制脉络膜血管指数并比较单侧中心性浆液性脉络膜视网膜病变（CSCR）患者的双眼情况。
这是一项针对单侧CSCR患者进行的回顾性观察研究。根据早期糖尿病视网膜病变（ETDRS）网格，在不同区域测量并绘制脉络膜厚度（CT）和脉络膜血管指数（CVI）。
本研究共纳入20例CSCR患者（20只患眼和20只对侧眼）。在CSCR患眼中，鼻外侧区域的CT明显低于中心CT（P = 0.042）和鼻内侧CT（P = 0.007）；外环CT明显小于中心CT（P = 0.04）和内环CT（P = 0.01）。将所有CVI值与相应的CT值进行绘制时，CSCR患眼中呈现正相关（r = 0.54，P < 0.01），对侧眼中相关性稍弱（r = 0.3，P < 0.01），而健康眼中呈现负相关（r = -0.262，P < 0.01）。
与对侧眼和正常眼相比，CSCR患眼中CVI与CT之间的相关性发生改变，在CSCR患眼中，CVI向黄斑中心和上方增加。
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