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中心性浆液性脉络膜视网膜病变:病理生理学与多模态成像的最新进展

Central serous chorioretinopathy: Current update on pathophysiology and multimodal imaging.

作者信息

Manayath George Joseph, Ranjan Ratnesh, Shah Vanee Sheth, Karandikar Smita S, Saravanan Veerappan R, Narendran Venkatapathy

机构信息

Department of Vitreo-Retina Services, Aravind Eye Hospital and Post-graduate Institute of Ophthalmology, Coimbatore, Tamilnadu, India.

出版信息

Oman J Ophthalmol. 2018 May-Aug;11(2):103-112. doi: 10.4103/ojo.OJO_75_2017.

Abstract

Central serous chorioretinopathy (CSC), the fourth most common nonsurgical retinopathy, is characterized by serous retinal detachment most commonly involving the macular region. Although natural history of CSC shows a self-limiting course, patients are known to present with persistent, recurrent, or even bilateral CSC with distressing visual loss. Multimodal imaging techniques for CSC include optical coherence tomography (OCT) with enhanced depth imaging, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, and OCT angiography. Evolution of new imaging techniques in addition to conventional imaging modalities has revolutionized the understanding about the pathophysiology of CSC and hence the diagnosis and management. This review article elaborates on current understanding about pathophysiology and risk factors, as well as multimodal imaging-based features of CSC.

摘要

中心性浆液性脉络膜视网膜病变(CSC)是第四种最常见的非手术性视网膜病变,其特征是浆液性视网膜脱离,最常累及黄斑区。尽管CSC的自然病程显示为自限性,但已知患者会出现持续性、复发性甚至双侧CSC,并伴有令人痛苦的视力丧失。CSC的多模态成像技术包括具有增强深度成像的光学相干断层扫描(OCT)、眼底自发荧光、荧光素血管造影、吲哚菁绿血管造影和OCT血管造影。除了传统成像方式外,新成像技术的发展彻底改变了对CSC病理生理学的理解,从而也改变了诊断和治疗方法。这篇综述文章阐述了目前对CSC病理生理学和危险因素的理解,以及基于多模态成像的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd01/5991069/4b8aa7bad939/OJO-11-103-g001.jpg

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